Spectroscopic sensors play a key role in process analytical technology. Such sensors can be interfaced to almost any type of manufacturing process, and by rapid, precise, and nondestructive spectroscopic analysis, it is possible to predict analyte concentration, quantify physical parameters, or fingerprint process streams and raw materials. The speed of modern spectroscopic instruments allows real-time process monitoring and control, and the ongoing development of miniaturized instruments and wireless communication now allows instruments to be placed directly on process equipment, which previously was not possible, for example, on rotating drums for mixing processes. Spectroscopic analyzers provide a real-time window into manufacturing processes that enables process control and inspection of intermediary and final product quality.The use of spectroscopy will continue to gain momentum in industrial manufacturing, as it is irreplaceable for ultrarapid process monitoring and control, and for 100% internal quality control necessary for tomorrow's individualized food and medicine.