Astaxanthin diferulate as a bifunctional antioxidant
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Abstract Astaxanthin when esterified with ferulic acid is better singlet oxygen quencher with k2 = (1.58 ± 0.1) 10(10) L mol(- 1)s(- 1) in ethanol at 25°C compared with astaxanthin with k2 = (1.12 ± 0.01) 10(9) L mol(- 1)s(- 1). The ferulate moiety in the astaxanthin diester is a better radical scavenger than free ferulic acid as seen from the rate constant of scavenging of 1-hydroxyethyl radicals in ethanol at 25°C with a second-order rate constant of (1.68 ± 0.1) 10(8) L mol(- 1)s(- 1) compared with (1.60 ± 0.03) 10(7) L mol(- 1)s(- 1) for the astaxanthin:ferulic acid mixture, 1:2 equivalents. The mutual enhancement of antioxidant activity for the newly synthetized astaxanthin diferulate becoming a bifunctional antioxidant is rationalized according to a two-dimensional classification plot for electron donation and electron acceptance capability.
Originalsprog | Engelsk |
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Tidsskrift | Free Radical Research |
Vol/bind | 49 |
Udgave nummer | 1 |
Sider (fra-til) | 102-111 |
Antal sider | 10 |
ISSN | 1071-5762 |
DOI | |
Status | Udgivet - 2015 |
ID: 128733855