Phase behavior of pure lipid bilayers with mismatch interactions
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Recently Corvera, Laradji, and Zuckermann (unpublished) showed that the multistate lattice model due to Pink, Green, and Chapman [Biochemistry 20, 6692 (1981)] with parameters obtained from fitting to thermodynamic data for saturated phospholipid bilayers does not exhibit a phase transition but could instead be described in terms of short-range fluctuations close to a critical point. We have extended the Pink-Green-Chapman model by including hydrophobic mismatch interactions between the lipid acyl-chain conformational states. We used Monte Carlo techniques to examine the phase behavior of the extended model and found that it exhibits first-order phase transitions above a critical value of the mismatch parameter. The results are discussed in relation to previous theoretical work as well as experimental measurements on lipid bilayers.
Originalsprog | Engelsk |
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Tidsskrift | Physical Review A - Atomic, Molecular, and Optical Physics |
Vol/bind | 45 |
Udgave nummer | 10 |
Sider (fra-til) | 7560-7567 |
Antal sider | 8 |
ISSN | 2469-9926 |
DOI | |
Status | Udgivet - 1992 |
Eksternt udgivet | Ja |
ID: 236892243