Dimensional profiling of psychopathology in children and adolescents based on the K-SADS-PL and an analysis of the construct validity of two ADHD symptom dimensions
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Dimensional profiling of psychopathology in children and adolescents based on the K-SADS-PL and an analysis of the construct validity of two ADHD symptom dimensions. / Hagstrøm, Julie; Nielsen, Tine; Sørensen, Mikkel E.; Aagaard, Kristina; Rasmussen, Morten Arendt; Rosenberg, Julie B.; Mohammadzadeh, Parisa; Sevelsted, Astrid; Hernández-lorca, María; Fagerlund, Birgitte; Rydkjær, Jacob; Pagsberg, Anne Katrine; Kaufman, Joan; Ebdrup, Bjørn H.; Bilenberg, Niels; Jepsen, Jens Richardt Møllegaard.
In: Nordic Journal of Psychiatry, Vol. 78, No. 1, 2024, p. 71-78 .Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Dimensional profiling of psychopathology in children and adolescents based on the K-SADS-PL and an analysis of the construct validity of two ADHD symptom dimensions
AU - Hagstrøm, Julie
AU - Nielsen, Tine
AU - Sørensen, Mikkel E.
AU - Aagaard, Kristina
AU - Rasmussen, Morten Arendt
AU - Rosenberg, Julie B.
AU - Mohammadzadeh, Parisa
AU - Sevelsted, Astrid
AU - Hernández-lorca, María
AU - Fagerlund, Birgitte
AU - Rydkjær, Jacob
AU - Pagsberg, Anne Katrine
AU - Kaufman, Joan
AU - Ebdrup, Bjørn H.
AU - Bilenberg, Niels
AU - Jepsen, Jens Richardt Møllegaard
PY - 2024
Y1 - 2024
N2 - Objectives: The traditional view on psychiatric disorders as categorical and distinct is being challenged by perspectives emphasizing the relevance of dimensional and transdiagnostic assessment. However, most diagnostic instruments are based on a categorical view with a threshold-approach to disease classification.Methods: We here describe algorithms for dimensionalizing the psychopathological ratings of the widely used diagnostic interview for children and adolescents, the Kiddie-Schedule for Affective Disorders and Schizophrenia – Present and Lifetime Version (K-SADS-PL). We further evaluate the criterion-related construct validity of the dimensionalized attention-deficit/hyperactivity disorder (ADHD) scales using Rasch models in a sample of 590 children (mean age 10.29 (.36), 49% girls).Results: The algorithms generate scores of current symptom load, i.e., the sum of clinician-rated symptoms within each disorder assessed with the interview. We found support for counting symptoms of inattention and hyperactivity/impulsivity, respectively, but not for a single combined ADHD scale.Conclusions: The algorithms constitute an initial step in creating a framework for clinician-rated dimensional analyses of symptoms derived from the K-SADS-PL, but future studies are needed to further evaluate the construct validity of the remaining scales and the reliability and clinical utility of the method. We believe that our proposed algorithms offer a novel method of dimensional psychopathological assessment, which can be applied in multiple branches of child and adolescent psychiatry.
AB - Objectives: The traditional view on psychiatric disorders as categorical and distinct is being challenged by perspectives emphasizing the relevance of dimensional and transdiagnostic assessment. However, most diagnostic instruments are based on a categorical view with a threshold-approach to disease classification.Methods: We here describe algorithms for dimensionalizing the psychopathological ratings of the widely used diagnostic interview for children and adolescents, the Kiddie-Schedule for Affective Disorders and Schizophrenia – Present and Lifetime Version (K-SADS-PL). We further evaluate the criterion-related construct validity of the dimensionalized attention-deficit/hyperactivity disorder (ADHD) scales using Rasch models in a sample of 590 children (mean age 10.29 (.36), 49% girls).Results: The algorithms generate scores of current symptom load, i.e., the sum of clinician-rated symptoms within each disorder assessed with the interview. We found support for counting symptoms of inattention and hyperactivity/impulsivity, respectively, but not for a single combined ADHD scale.Conclusions: The algorithms constitute an initial step in creating a framework for clinician-rated dimensional analyses of symptoms derived from the K-SADS-PL, but future studies are needed to further evaluate the construct validity of the remaining scales and the reliability and clinical utility of the method. We believe that our proposed algorithms offer a novel method of dimensional psychopathological assessment, which can be applied in multiple branches of child and adolescent psychiatry.
U2 - 10.1080/08039488.2023.2262997
DO - 10.1080/08039488.2023.2262997
M3 - Journal article
C2 - 37755235
VL - 78
SP - 71
EP - 78
JO - Nordic Journal of Psychiatry, Supplement
JF - Nordic Journal of Psychiatry, Supplement
SN - 0803-9496
IS - 1
ER -
ID: 369176955