Citrate in calcium transport and biomineralisation

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Citrate in calcium transport and biomineralisation. / Liu, Xiao Chen; Skibsted, Leif H.

In: International Dairy Journal, Vol. 139, 105561, 2023.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Liu, XC & Skibsted, LH 2023, 'Citrate in calcium transport and biomineralisation', International Dairy Journal, vol. 139, 105561. https://doi.org/10.1016/j.idairyj.2022.105561

APA

Liu, X. C., & Skibsted, L. H. (2023). Citrate in calcium transport and biomineralisation. International Dairy Journal, 139, [105561]. https://doi.org/10.1016/j.idairyj.2022.105561

Vancouver

Liu XC, Skibsted LH. Citrate in calcium transport and biomineralisation. International Dairy Journal. 2023;139. 105561. https://doi.org/10.1016/j.idairyj.2022.105561

Author

Liu, Xiao Chen ; Skibsted, Leif H. / Citrate in calcium transport and biomineralisation. In: International Dairy Journal. 2023 ; Vol. 139.

Bibtex

@article{4d61b56e2b9549d2ba271f2d7d22559c,
title = "Citrate in calcium transport and biomineralisation",
abstract = "Citrates increase calcium bioavailability from food and beverages such as milk and are important for transport of calcium during calcium phosphate biomineralisation in mammal skeletons. Long-lasting spontaneous supersaturation of calcium citrate in presence of excess citrate or isocitrate counteracts the low aqueous solubility otherwise limiting calcium transport with isocitrate as a growth inhibitor for calcium citrate crystallisation and citrate as a growth inhibitor for calcium isocitrate crystallisation. The aim of this present review is to understand why the metastable calcium citrate tetrahydrate of higher solubility becomes important for bioavailability and for mineralisation under physiological conditions rather than the stable hexahydrate of lower solubility. Transformation from the tetrahydrate is kinetically hindered by trapping into a polymorph tetrahydrate with four water molecules bound in the first coordination sphere of calcium.",
author = "Liu, {Xiao Chen} and Skibsted, {Leif H.}",
note = "Publisher Copyright: {\textcopyright} 2022 The Author(s)",
year = "2023",
doi = "10.1016/j.idairyj.2022.105561",
language = "English",
volume = "139",
journal = "International Dairy Journal",
issn = "0958-6946",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Citrate in calcium transport and biomineralisation

AU - Liu, Xiao Chen

AU - Skibsted, Leif H.

N1 - Publisher Copyright: © 2022 The Author(s)

PY - 2023

Y1 - 2023

N2 - Citrates increase calcium bioavailability from food and beverages such as milk and are important for transport of calcium during calcium phosphate biomineralisation in mammal skeletons. Long-lasting spontaneous supersaturation of calcium citrate in presence of excess citrate or isocitrate counteracts the low aqueous solubility otherwise limiting calcium transport with isocitrate as a growth inhibitor for calcium citrate crystallisation and citrate as a growth inhibitor for calcium isocitrate crystallisation. The aim of this present review is to understand why the metastable calcium citrate tetrahydrate of higher solubility becomes important for bioavailability and for mineralisation under physiological conditions rather than the stable hexahydrate of lower solubility. Transformation from the tetrahydrate is kinetically hindered by trapping into a polymorph tetrahydrate with four water molecules bound in the first coordination sphere of calcium.

AB - Citrates increase calcium bioavailability from food and beverages such as milk and are important for transport of calcium during calcium phosphate biomineralisation in mammal skeletons. Long-lasting spontaneous supersaturation of calcium citrate in presence of excess citrate or isocitrate counteracts the low aqueous solubility otherwise limiting calcium transport with isocitrate as a growth inhibitor for calcium citrate crystallisation and citrate as a growth inhibitor for calcium isocitrate crystallisation. The aim of this present review is to understand why the metastable calcium citrate tetrahydrate of higher solubility becomes important for bioavailability and for mineralisation under physiological conditions rather than the stable hexahydrate of lower solubility. Transformation from the tetrahydrate is kinetically hindered by trapping into a polymorph tetrahydrate with four water molecules bound in the first coordination sphere of calcium.

U2 - 10.1016/j.idairyj.2022.105561

DO - 10.1016/j.idairyj.2022.105561

M3 - Review

AN - SCOPUS:85144603319

VL - 139

JO - International Dairy Journal

JF - International Dairy Journal

SN - 0958-6946

M1 - 105561

ER -

ID: 331586335