Biopolymer Based Food Delivery Systems - BIBAFOODS

An Initial Training Network (ITN) funded by the FP7-PEOPLE-2013 programme

Project period:1 February 2014 – 31 January 2018

The aim of BIBAFOODS is to train young researchers in developing colloidal delivery systems to protect and deliver active components via foods, resulting in novel functional foods.

Materials and coatings can be made responsive to the external chemical conditions and therefore suitable for controlled releases targeted at a desired stage during food processing or at a specific point during digestion of the food, e.g. in the intestinal tract. This will involve probiotic bacteria and enzymes that are liberated and allowed to be active in a controllable way. The ultimate successful materials ensure stability of the active component during long-term storage prior to food production, during food production or during digestion, but at the same time liberating the active component at the right point.

The behavior and interaction of the delivery systems will be studied by simulation of gastric and intestinal conditions and by implementation in food production and formulation into probiotic products.

The researchers trained in BIBAFOODS will obtain skills necessary for the development of the sustainable food industry, and they will be provided with entrepreneurial competences crucial for creating biotechnological food oriented start-up companies.

















Scientific articles

A.P. Dabkowska, C. Hirst, M. Valldeperas, L.A. Clifton, C. Montis, S. Nöjd,
L. Gentile, M. Wang, G.K. Pálsson, S. Lages, D. Berti, J. Barauskas, T. Nylander
(2017): Temperature responsive lipid liquid crystal layers with embedded nanogels. Chem. Commun., 53, p. 1417-1420. DOI: 10.1039/C6CC09426K.

Roudayna Diab, Nadia Canilho, Ileana A. Pavel, Fernanda B.  Haffner, Maxime Girardon, Andreea Pasc (2017); Silica-based systems for oral delivery of drugs, macromolecules and cells. Advances in Colloid and interface Science In press. DOI:

Cigdem Yucel Falco, Peter Falkman, Jens Risbo, Marité Cárdenas, Bruno Medronho (2017): Chitosan-dextran sulfate hydrogels as a potential carrier for probiotics. Carbohydrate Polymers, 172, p. 175-183. DOI:

Cigdem Yucel Falco, Xiaolu Geng, Marité Cárdenas, Jens Risbo (2017): Edible foam based on Pickering effect of probiotic bacteria and milk proteins. Food Hydrocolloids 70, p. 211–218. DOI:

Cigdem Yucel Falco, Javier Sotres, Ana Rascón, Jens Risbo, Marité Cárdenas (2017):
Design of a potentially prebiotic and responsive encapsulation material for probiotic bacteria based on chitosan and sulfated β-glucan. Journal of Colloid and Interface Science 487, p. 97-106. DOI: 10.1016/j.jcis.2016.10.019.

D. Gottardi, P. Van den Abbeele, M. Marzorati (2016): Use of the simulator of the human intestinal microbial ecosystem (SHIME®) to study the fate of food ingredients and actives. Agro FOOD Industry Hi Tech 27(5), p. XXII-XXIV.

Fernanda B. Haffner, Roudayna Diab, Andreea Pasc (2016): Encapsulation of probiotics: insights into academic and industrial approaches. AIMS Materials Science 3(1), p. 114-136. DOI: 10.3934/matersci.2016.1.114.

Fernanda B. Haffner, Maxime Girardon, Mathieu Etienne, Stephane Fontanay, Nadia Canilho, Raphael E Duval, Maciej Mierzwa, Roudayna Diab, Andreea Pasc (2016): Core-shell alginate@silica microparticles encapsulating probiotics. J. Mater. Chem. B 4, p. 7929-7935. DOI: 10.1039/C6TB02802K.

Agatha Korytowski, Wassim Abuillan, Federico Amadei, Ali Makky, Andrea Gumiero, Irmgard Sinning, Annika Gauss, Wolfgang Stremmel, Motomu Tanaka (2017): Accumulation of phosphatidylcholine on gut mucosal surface is not dominated by electrostatic interactions. Biochimica et Biophysica Acta 1859, p. 959-965. DOI: 10.1016/j.bbamem.2017.02.008.

Ileana-Alexandra Pavel, Sofia F. Prazeres, Gemma Montalvo, Carmen García Ruiz, Vincent Nicolas, Alain Celzard, Francois Dehez, Laetitia Canabady-Rochelle, Nadia Canilho, Andreea Pasc (2017): Effect of meso and macro size of hierarchical porous silica on the adsorption and activity of immobilized β-galactosidase. Langmuir 33, p. 3333-3340. DOI: 10.1021/acs.langmuir.7b00134.

Sofia Prazeres, Carmen García Ruiz and Gemma Montalvo García (2015): Vibrational Spectroscopy as Promising Tool to Study Enzyme-Carrier Interactions: A review. Applied Spectroscopy Reviews 50, p. 797-821. 

Carina Svendsen, Tomasz Cieplak, Frans W.J. van den Berg (2016): Exploring process dynamics by near infrared spectroscopy in lactic fermentations. Journal of Near Infrared Spectroscopy 24, p. 443-451.

Maria Valldeperas, Małgorzata Wiśniewska, Maor Ram-On, Ellina Kesselman, Dganit Danino, Tommy Nylander, and Justas Barauskas (2016): Sponge Phases and Nanoparticle Dispersions in Aqueous Mixtures of Mono- and Diglycerides. Langmuir 32(34), p. 8650−8659. 

Book chapters

Poonam Singh, Hugo Duarte, Luís Alves, Filipe Antunes, Nicolas Le Moigne, Jan Dormanns, Benoît Duchemin, Mark P. Staiger and Bruno Medronho (2015). From Cellulose Dissolution and Regeneration to Added Value Applications — Synergism Between Molecular Understanding and Material Development, Cellulose - Fundamental Aspects and Current Trends, Dr. Matheus Poletto (Ed.), ISBN: 978-953-51-2229-6, InTech, DOI: 10.5772/61402.


Interview (in French) with Ileana Pavel and Fernanda Haffner in Factuel, a news website at University of Lorraine, 12 November 2014:

Interview (in Spanish) with Sofia Prazeres, Gemma Montalvo and Carmen García Ruíz in ‘Diario Digital da Universidad de Alcalá’, 14th November 2014:






The project was funded by:

EU Logo

This project has received funding from the European Union's Seventh Framework Programme for research, technological development and demonstration under grant agreement no 606713 

Funding: EUR 3,765,084