Bekzod Khakimov
Associate Professor
- 2012
- Published
Plant metabolomics: resolution and quantification of elusive peaks in liquid chromatography–mass spectrometry profiles of complex plant extracts using multi-way decomposition methods
Khakimov, Bekzod, Amigo Rubio, J. M., Bak, Søren & Engelsen, Søren Balling, 2012, In: Journal of Chromatography A. 1266, p. 84-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plante-metabolomics: opdagelse af nye bioaktive stoffer med PARAFAC2
Khakimov, Bekzod, Engelsen, Søren Balling, Bro, Rasmus & Nørgaard, L., 2012, In: Dansk Kemi. 93, 12, p. 29-31 3 p.Research output: Contribution to journal › Journal article › Research
- Published
UDP-glycosyltransferases from the UGT73C subfamily in Barbarea vulgaris catalyse Sapogenin 3-O-glucosylation in Saponin-mediated Insect resistance
Augustin, J. M., Drok, S., Shinoda, T., Sanmiya, K., Nielsen, J. K., Khakimov, Bekzod, Olsen, C. E., Hansen, E. H., Poulsen, V. K., Ekstrøm, Claus Thorn, Hauser, T. P. & Bak, Søren, 2012, In: Plant Physiology. 160, 4, p. 1881-1895 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Metabolomics and bioactive substances in plants
Khakimov, Bekzod, 2013, Department of Food Science, University of Copenhagen. 262 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
The use of trimethylsilyl cyanide derivatization for robust and broad-spectrum high-throughput gas chromatography–mass spectrometry based metabolomics
Khakimov, Bekzod, Motawie, Mohammed Saddik, Bak, Søren & Engelsen, Søren Balling, 2013, In: Analytical and Bioanalytical Chemistry. 405, 28, p. 9193-9205 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Comprehensive and comparative metabolomic profiling of wheat, barley, oat and rye using gas chromatography-mass spectrometry and advanced chemometrics
Khakimov, Bekzod, Jespersen, Birthe P Møller & Engelsen, Søren Balling, 2014, In: Foods. 3, 4, p. 569-585 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-throughput cereal metabolomics: current analytical technologies, challenges and perspectives
Khakimov, Bekzod, Bak, Søren & Engelsen, Søren Balling, 2014, In: Journal of Cereal Science. 59, 3, p. 393-418 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana
Khakimov, Bekzod, Poulsen, V. K., Erthmann, P. Ø., Fukushima, E. O., Augustin, J. M., Olsen, C. E., Scholtalbers, J., Volpin, H., Andersen, S. B., Hauser, T. P., Muranaka, T. & Bak, Søren, 2015, In: The Plant Journal. 84, 3, p. 478-490 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trends in the application of chemometrics to foodomics studies
Khakimov, Bekzod, Gürdeniz, G. & Engelsen, Søren Balling, 2015, In: Acta Alimentaria. 44, 1, p. 4-31 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
A comprehensive and comparative GC-MS metabolomics study of non-volatiles in Tanzanian grown mango, pineapple, jackfruit, baobab and tamarind fruits
Khakimov, Bekzod, Mongi, R. J., Sørensen, Klavs Martin, Ndabikunze, B. K., Chove, B. E. & Engelsen, Søren Balling, 2016, In: Food Chemistry. 213, p. 691-699 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Counteracting age-related loss of skeletal muscle mass: a clinical and ethnological trial on the role of protein supplementation and training load (CALM Intervention Study): study protocol for a randomized controlled trial
Bechshøft, R., Reitelseder, S., Højfeldt, Grith Stougaard, Castro Mejia, J. L., Khakimov, Bekzod, Bin Ahmad, H. F., Kjær, Michael, Engelsen, Søren Balling, Laugesen, S. M. B., Rasmussen, Morten Arendt, Lassen, Aske Juul, Jensen, T., Beyer, N., Serena, A., Perez-Cueto, Federico J.A., Nielsen, Dennis Sandris, Jespersen, Astrid Pernille & Holm, L., 2016, In: Trials. 17, 17 p., 397.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GC-MS metabolite profiling of extreme southern Pinot noir wines: effects of vintage, barrel maturation, and fermentation dominate over vineyard site and clone selection
Schueuermann, C., Khakimov, Bekzod, Engelsen, Søren Balling, Bremer, P. & Silcock, P., 2016, In: Journal of Agricultural and Food Chemistry. 64, 11, p. 2342-2351 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators
Pentzold, S., Zagrobelny, Mika, Khakimov, Bekzod, Engelsen, Søren Balling, Clausen, Henrik, Petersen, Bent L, Borch, J., Møller, Birger Lindberg & Bak, Søren, 2016, In: Scientific Reports. 6, 11 p., 22407 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New Nordic diet versus average Danish diet: a randomized controlled trial revealed healthy long-term effects of the new Nordic diet by GC-MS blood plasma metabolomics
Khakimov, Bekzod, Poulsen, S. K., Savorani, F., Evrim, A. A., Gürdeniz, G., Larsen, T. M., Astrup, A., Dragsted, Lars Ove & Engelsen, Søren Balling, 2016, In: Journal of Proteome Research. 15, 6, p. 1939-1954 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening for triterpenoid saponins in plants using hyphenated analytical platforms
Khakimov, Bekzod, Tseng, L. H., Godejohann, M., Bak, Søren & Engelsen, Søren Balling, 2016, In: Molecules. 21, 12, 19 p., 1614.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The use of rapid spectroscopic screening methods to detect adulteration of food raw materials and ingredients
Sørensen, Klavs Martin, Khakimov, Bekzod & Engelsen, Søren Balling, 2016, In: Current Opinion in Food Science. 10, p. 45-51 7 p.Research output: Contribution to journal › Review › Research › peer-review
- 2017
- Published
Antibiotic treatment preventing necrotising enterocolitis alters urinary and plasma metabolomes in preterm pigs
Jiang, Pingping, Trimigno, A., Stanstrup, Jan, Khakimov, Bekzod, Viereck, Nanna, Engelsen, Søren Balling, Sangild, Per Torp & Dragsted, Lars Ove, 2017, In: Journal of Proteome Research. 16, p. 3547-3557 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From metabolome to phenotype: GC-MS metabolomics of developing mutant barley seeds reveals effects of growth, temperature and genotype
Khakimov, Bekzod, Rasmussen, Morten Arendt, Kannangara, R. M., Jespersen, Birthe P Møller, Munck, L. & Engelsen, Søren Balling, 2017, In: Scientific Reports. 7, 1, 12 p., 8195.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gas chromatography – mass spectrometry data processing made easy
Johnsen, L. G., Skou, P. B., Khakimov, Bekzod & Bro, Rasmus, 2017, In: Journal of Chromatography A. 1503, p. 57-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of weak and gender specific effects in a short 3 weeks intervention study using barley and oat mixed linkage β-glucan dietary supplements: a human fecal metabolome study by GC-MS
Trimigno, A., Khakimov, Bekzod, Castro Mejia, J. L., Mikkelsen, M. S., Kristensen, M. B., Jespersen, Birthe P Møller & Engelsen, Søren Balling, 2017, In: Metabolomics. 13, 13 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and structural characterization of echinocystic acid triterpenoid saponins from the Australian medicinal and food plant Acacia ligulata
Knudsen, D. J., Ndi, C. P., Crocoll, C., Simpson, B. S., Khakimov, Bekzod, Guzman-Genuino, R. M., Hayball, J. D., Xing, X., Bulone, V., Weinstein, P., Møller, Birger Lindberg & Semple, S. J., 2017, In: Journal of Natural Products. 80, 10, p. 2692-2698 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of lipoprotein profiles by nuclear magnetic resonance spectroscopy and multivariate data analysis
Aru, Violetta, Lam, C., Khakimov, Bekzod, Hoefsloot, H. C. J., Zwanenburg, G., Lind, M. V., Schäfer, H., van Duynhoven, J., Jacobs, D. M., Smilde, A. K. & Engelsen, Søren Balling, 2017, In: Trends in Analytical Chemistry. 94, p. 210-219 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quinoa seed coats as an expanding and sustainable source of bioactive compounds: an investigation of genotypic diversity in saponin profiles
Ruiz, K. B., Khakimov, Bekzod, Engelsen, Søren Balling, Bak, Søren, Biondi, S. & Jacobsen, S., 2017, In: Industrial Crops and Products. 104, p. 156-163 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resveratrol in the foodomics era: 1:25,000
Khakimov, Bekzod & Engelsen, Søren Balling, 2017, In: New York Academy of Sciences. Annals. 1403, 1, p. 48-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toward Reliable Lipoprotein Particle Predictions from NMR Spectra of Human Blood: An Interlaboratory Ring Test
Centelles, S. M., Hoefsloot, H. C. J., Khakimov, Bekzod, Ebrahimi, Parvaneh, Lind, M. V., Kristensen, M., de Roo, N., Jacobs, D. M., van Duynhoven, J., Gannet, C., Fang, F., Humpfer, E., Schaefer, H., Spraul, M., Engelsen, Søren Balling & Smilde, A. K., 2017, In: Analytical Chemistry. 89, 15, p. 8004-8012 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Untargeted GC-MS Metabolomics Reveals Changes in the Metabolite Dynamics of Industrial Scale Batch Fermentations of Streptoccoccus thermophilus Broth
Khakimov, Bekzod, Christiansen, L. D., Heins, A., Sørensen, Klavs Martin, Scholler, C., Clausen, A., Skov, T., Gernaey, K. V. & Engelsen, Søren Balling, 2017, In: Biotechnology Journal. 12, 10, 9 p., 1700400.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin
Almeida, A., Dong, L., Khakimov, Bekzod, Bassard, J. A., Moses, T., Lota, F., Goossens, A., Appendino, G. & Bak, Søren, 2018, In: Plant Physiology. 176, 2, p. 1469-1484 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biogenic amines: a key freshness parameter of animal protein products in the coming circular economy
Sørensen, Klavs Martin, Aru, Violetta, Khakimov, Bekzod, Aunskjaer, U. & Engelsen, Søren Balling, 2018, In: Current Opinion in Food Science. 22, p. 167-173Research output: Contribution to journal › Review › Research › peer-review
- Published
Chemical characterization by gas chromatography-mass spectrometry and inductively coupled plasma-optical emissionn spectroscopy of membrane permeates from an industrial dairy ingredient production used as process water
Skou, P. B., Khakimov, Bekzod, Hansen, Thomas Hesselhøj, Aunsbjerg, S. D., Knoechel, Susanne, Thaysen, D. & van der Berg, Franciscus Winfried J, 2018, In: Journal of Dairy Science. 101, 1, p. 135-146 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast
Dong, L., Pollier, J., Bassard, J., Ntallas, G., Almeida, A., Lazaridi, E., Khakimov, Bekzod, Arendt, P., de Oliveira, L. S., Lota, F., Goossens, A., Michoux, F. & Bak, Søren, 2018, In: Metabolic Engineering. 49, p. 1-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CoMiniGut - a small volume in vitro colon model for the screening of gut microbial fermentation processes
Wiese, M., Khakimov, Bekzod, Nielsen, S., Sørensen, H., van der Berg, Franciscus Winfried J & Nielsen, Dennis Sandris, 2018, In: PeerJ. 6, 22 p., e4268.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cool-climate red wines - Chemical Composition and Camparison of two protocols for 1H-NMR Analysis
Aru, Violetta, Sørensen, Klavs Martin, Khakimov, Bekzod, Toldam-Andersen, Torben & Engelsen, Søren Balling, 2018, In: Molecules. 23, 160, p. 1-18 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NMR Foodomics
Savorani, F., Khakimov, Bekzod, Viereck, Nanna & Engelsen, Søren Balling, 2018, NMR-based Metabolomics. Keun, H. C. (ed.). Royal Society of Chemistry, p. 183-245 63 p. (New Developments in NMR, Vol. 14).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The foodome of bivalve molluscs: From hedonic eating to healthy diet
Aru, Violetta, Khakimov, Bekzod, Sørensen, Klavs Martin & Engelsen, Søren Balling, 2018, In: Journal of Food Composition and Analysis. 69, p. 13-19 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Biomarkers of individual foods, and separation of diets using untargeted LC-MS-based plasma metabolomics in a randomized controlled trial
Acar, E., Gürdeniz, G., Khakimov, Bekzod, Savorani, F., Korndal, S. K., Larsen, T. M., Engelsen, Søren Balling, Astrup, A. & Dragsted, Lars Ove, 2019, In: Molecular Nutrition & Food Research. 63, 1, 10 p., 1800215.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of fecal microbiota transplantation route of administration on gut colonization and host response in preterm pigs
Brunse, Anders, Martin, L., Rasmussen, Torben Sølbeck, Christensen, Lars, Cilieborg, Malene Skovsted, Wiese, M., Khakimov, Bekzod, Pieper, R., Nielsen, Dennis Sandris, Sangild, Per Torp & Thymann, Thomas, 2019, In: ISME Journal. 13, p. 720–733Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of Variations in the Human Urine Metabolome amongst European Populations: An Exploratory Search for Biomarkers of People at Risk-of-Poverty
Trimigno, A., Khakimov, Bekzod, Savorani, F., Tenori, L., Hendrixson, V., Civilis, A., Glibetic, M., Gurinovic, M., Pentikäinen, S., Sallinen, J., Diaz, S. G., Pasqui, F., Khokhar, S., Luchinat, C., Bordoni, A., Capozzi, F. & Engelsen, Søren Balling, 2019, In: Molecular Nutrition & Food Research. 63, 1, p. 1-11 1800216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of charcoal on medicinal compounds of seeds of fenugreek (Trigonella foenum-graecum L.) exposed to drought stress
Bitarafan, Z., Asghari, H. R., Hasanloo, T., Gholami, A., Moradi, F., Khakimov, Bekzod, Liu, Fulai & Andreasen, Christian, 2019, In: Industrial Crops and Products. 131, p. 323-329Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cytochrome P450 CYP72A552 is key to production of hederagenin‐based saponins that mediate plant defense against herbivores
Liu, Q., Khakimov, Bekzod, Cárdenas, Pablo D., Cozzi, F., Olsen, C. E., Jensen, Karen Rysbjerg, Hauser, T. P. & Bak, Søren, May 2019, In: New Phytologist (Online). 222, 3, p. 1599-1609Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A Multi-Omics Approach Reveals New Signatures in Obese Allergic Asthmatic Children
Gomez-Llorente, M. A., Martínez-Cañavate, A., Chueca, N., Rico, M. D. L. C., Romero, R., Anguita-Ruiz, A., Aguilera, C. M., Gil-Campos, M., Mesa, M. D., Khakimov, Bekzod, Morillo, J. A., Gil, Á., Camacho, J. & Gomez-Llorente, C., 2020, In: Biomedicines. 8, 9, 16 p., 359.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of statistical methods for predicting penetration capacity of drugs into human breast milk using physicochemical, pharmacokinetic and chromatographic descriptors
Wanat, K., Khakimov, Bekzod & Brzezinska, E., 2020, In: SAR and QSAR in Environmental Research. 31, 6, p. 457-475 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-principles identification of C-methyl-scyllo-inositol (mytilitol) – A new species-specific metabolite indicator of geographic origin for marine bivalve molluscs (Mytilus and Ruditapes spp.)
Aru, Violetta, Motawie, Mohammed Saddik, Khakimov, Bekzod, Sørensen, Klavs Martin, Møller, Birger Lindberg & Engelsen, Søren Balling, 2020, In: Food Chemistry. 328, 7 p., 126959.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Faecal 1H NMR Metabolomics: Evaluation of Solvent and Sample Processing on Coverage and Reproducibility of Signature Metabolites
Cui, M., Trimigno, A., Aru, Violetta, Khakimov, Bekzod & Engelsen, Søren Balling, 2020, In: Analytical Chemistry. 92, 14, p. 9546-9555 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human urine 1H NMR metabolomics reveals alterations of the protein and carbohydrate metabolism when comparing habitual Average Danish diet vs. healthy New Nordic diet
Trimigno, A., Khakimov, Bekzod, Savorani, F., Poulsen, S. K., Astrup, A., Dragsted, Lars Ove & Engelsen, Søren Balling, 2020, In: Nutrition. 79-80, 11 p., 110867.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IDDF2020-ABS-0174 Onset of hypertriglyceridemia in relation to dietary intake, gut microbiome and metabolomics signatures among home dwelling elderly
Ahmad, H. F., Mejia, J. L. C., Krych, Lukasz, Khakimov, Bekzod, Kot, W., Bechshoft, R. L., Reitelseder, S., Engelsen, Søren Balling, Holm, L. & Faust, K., 2020, In: Gut. 69, Suppl 2, p. A21-A21 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Physical fitness in community-dwelling older adults is linked to dietary intake, gut microbiota, and metabolomic signatures
Castro-Mejia, J. L., Khakimov, B., Krych, L., Bülow, J., Bechshøft, R. L., Højfeldt, G., Mertz, K. H., Garne, E. S., Schacht, S. R., Ahmad, H. F., Kot, W., Hansen, L. H., Perez-Cueto, F. J. A., Lind, M. V., Lassen, A. J., Tetens, I., Jensen, T., Reitelseder, S., Jespersen, A. P., Holm, L. & 2 others, , 2020, In: Aging Cell. 19, 3, 13 p., e13105.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signature Mapping (SigMa): an efficient approach for processing complex human urine 1H NMR metabolomics data
Khakimov, Bekzod, Mobaraki, N., Trimigno, A., Aru, Violetta & Engelsen, Søren Balling, 2020, In: Analytica Chimica Acta. 1108, p. 142-151 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structurally different mixed linkage β-glucan supplements differentially increase secondary bile acid excretion in hypercholesterolaemic rat faeces
Iaccarino, N., Khakimov, Bekzod, Mikkelsen, M. S., Nielsen, T. S., Jensen, M. G., Randazzo, A. & Engelsen, Søren Balling, 2020, In: Food & Function. 11, 1, p. 514-523Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthetic Biology of Cannabinoids and Cannabinoid Glucosides in Nicotiana benthamiana and Saccharomyces cerevisiae
Gülck, T., Booth, J. K., Carvalho, Â., Khakimov, Bekzod, Crocoll, C., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Bohlmann, J. & Gallage, N. J., 2020, In: Journal of Natural Products. 83, 10, p. 2877-2893 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara
Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 21326016
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UDP-glycosyltransferases from the UGT73C subfamily in Barbarea vulgaris catalyse Sapogenin 3-O-glucosylation in Saponin-mediated Insect resistance
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
909
downloads
Comprehensive and comparative metabolomic profiling of wheat, barley, oat and rye using gas chromatography-mass spectrometry and advanced chemometrics
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
626
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Counteracting age-related loss of skeletal muscle mass: a clinical and ethnological trial on the role of protein supplementation and training load (CALM Intervention Study): study protocol for a randomized controlled trial
Research output: Contribution to journal › Journal article › Research › peer-review
Published