Metabolic footprint of Lactobacillus acidophilus NCFM at different pH
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Metabolic footprint of Lactobacillus acidophilus NCFM at different pH. / Sulek, Karolina; Frandsen, Henrik Lauritz; Smedsgaard, Jorn; Skov, Thomas Hjort; Wilcks, Andrea; Licht, Tine Rask.
In: Metabolomics, Vol. 8, No. 2, 2012, p. 244-252.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Metabolic footprint of Lactobacillus acidophilus NCFM at different pH
AU - Sulek, Karolina
AU - Frandsen, Henrik Lauritz
AU - Smedsgaard, Jorn
AU - Skov, Thomas Hjort
AU - Wilcks, Andrea
AU - Licht, Tine Rask
PY - 2012
Y1 - 2012
N2 - Lactobacillus acidophilus NCFM is a well known microorganism from the genomic and probiotic point of view. In order to analyze the potential interactions of NCFM with the surrounding environment, in vitro tests with the metabolic footprinting approach were performed. It was found that NCFM increased the concentration of lactic acid, succinic acid, adenine and arginine in the medium. The metabolism of NCFM did not change significantly between pH 5 and 7, suggesting that other environmental factors than pH might have bigger impact on its colonization throughout the gastrointestinal tract.
AB - Lactobacillus acidophilus NCFM is a well known microorganism from the genomic and probiotic point of view. In order to analyze the potential interactions of NCFM with the surrounding environment, in vitro tests with the metabolic footprinting approach were performed. It was found that NCFM increased the concentration of lactic acid, succinic acid, adenine and arginine in the medium. The metabolism of NCFM did not change significantly between pH 5 and 7, suggesting that other environmental factors than pH might have bigger impact on its colonization throughout the gastrointestinal tract.
U2 - 10.1007/s11306-011-0305-4
DO - 10.1007/s11306-011-0305-4
M3 - Journal article
VL - 8
SP - 244
EP - 252
JO - Metabolomics
JF - Metabolomics
SN - 1573-3882
IS - 2
ER -
ID: 49640275