Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats
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Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats. / Fotschki, Bartosz; Juśkiewicz, Jerzy; Jurgoński, Adam; Amarowicz, Ryszard; Opyd, Paulina; Bez, Jürgen; Muranyi, Isabel; Petersen, Iben Lykke; Llopis, Moisés Laparra.
In: Nutrients, Vol. 12, No. 9, 2781, 2020.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - Protein-Rich Flours from Quinoa and Buckwheat Favourably Affect the Growth Parameters, Intestinal Microbial Activity and Plasma Lipid Profile of Rats
AU - Fotschki, Bartosz
AU - Juśkiewicz, Jerzy
AU - Jurgoński, Adam
AU - Amarowicz, Ryszard
AU - Opyd, Paulina
AU - Bez, Jürgen
AU - Muranyi, Isabel
AU - Petersen, Iben Lykke
AU - Llopis, Moisés Laparra
PY - 2020
Y1 - 2020
N2 - In recent years, dietary products with quinoa and buckwheat have attracted attention mostly due to the high nutritive value of their protein fraction. However, their dietary effect on intestinal microbiota activity and related systemic responses are still poorly understood. Therefore, a 2 week study of twenty-eight growing male Wistar rats was conducted to investigate the effects of quinoa (QU) and buckwheat (BK) protein-rich flours on the growth parameters, intestinal microbial activity, plasma lipid profile, and inflammatory markers. The biological value of protein and body weight gain were considerably increased in the QU and BK groups compared with those in the soy protein isolate group. Moreover, both flours increased the microbial activity of α-glucosidase, β-glucosidase, and α-galactosidase and the concentration of short-chain fatty acids in the caecum. The studied flours favourably reduced the plasma total cholesterol and LDL cholesterol. In rats fed a diet with QU, elevated levels of plasma interleukin 6 and alanine transaminase were observed. The effect of QU on inflammatory markers may be related to the increased expression of aryl hydrocarbon receptor in the liver and to the decreased level of plasma albumin. In conclusion, quinoa and buckwheat protein-rich flours are valuable sources of proteins that favourably affect growth parameters, gut metabolism, and blood lipid profile in rats; however, only the buckwheat flour has no effect on inflammatory processes.
AB - In recent years, dietary products with quinoa and buckwheat have attracted attention mostly due to the high nutritive value of their protein fraction. However, their dietary effect on intestinal microbiota activity and related systemic responses are still poorly understood. Therefore, a 2 week study of twenty-eight growing male Wistar rats was conducted to investigate the effects of quinoa (QU) and buckwheat (BK) protein-rich flours on the growth parameters, intestinal microbial activity, plasma lipid profile, and inflammatory markers. The biological value of protein and body weight gain were considerably increased in the QU and BK groups compared with those in the soy protein isolate group. Moreover, both flours increased the microbial activity of α-glucosidase, β-glucosidase, and α-galactosidase and the concentration of short-chain fatty acids in the caecum. The studied flours favourably reduced the plasma total cholesterol and LDL cholesterol. In rats fed a diet with QU, elevated levels of plasma interleukin 6 and alanine transaminase were observed. The effect of QU on inflammatory markers may be related to the increased expression of aryl hydrocarbon receptor in the liver and to the decreased level of plasma albumin. In conclusion, quinoa and buckwheat protein-rich flours are valuable sources of proteins that favourably affect growth parameters, gut metabolism, and blood lipid profile in rats; however, only the buckwheat flour has no effect on inflammatory processes.
KW - Aryl hydrocarbon receptor
KW - Buckwheat
KW - Butyric acid
KW - Lipid profile
KW - Quinoa
KW - Wistar rats
U2 - 10.3390/nu12092781
DO - 10.3390/nu12092781
M3 - Journal article
C2 - 32932953
AN - SCOPUS:85090597783
VL - 12
JO - Nutrients
JF - Nutrients
SN - 2072-6643
IS - 9
M1 - 2781
ER -
ID: 249767589