Problems and paradigms: Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for membrane function?

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Problems and paradigms: Dynamic lipid-bilayer heterogeneity : A mesoscopic vehicle for membrane function? / Mouritsen, Ole G.; Jørgensen, Kent.

In: BioEssays, Vol. 14, No. 2, 1992, p. 129-136.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Mouritsen, OG & Jørgensen, K 1992, 'Problems and paradigms: Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for membrane function?', BioEssays, vol. 14, no. 2, pp. 129-136. https://doi.org/10.1002/bies.950140211

APA

Mouritsen, O. G., & Jørgensen, K. (1992). Problems and paradigms: Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for membrane function? BioEssays, 14(2), 129-136. https://doi.org/10.1002/bies.950140211

Vancouver

Mouritsen OG, Jørgensen K. Problems and paradigms: Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for membrane function? BioEssays. 1992;14(2):129-136. https://doi.org/10.1002/bies.950140211

Author

Mouritsen, Ole G. ; Jørgensen, Kent. / Problems and paradigms: Dynamic lipid-bilayer heterogeneity : A mesoscopic vehicle for membrane function?. In: BioEssays. 1992 ; Vol. 14, No. 2. pp. 129-136.

Bibtex

@article{4929c41d5726468da24cd74773c2aca2,
title = "Problems and paradigms: Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for membrane function?",
abstract = "The lipid-bilayer component of cell membranes is an aqueous bimolecular aggregate characterized by a heterogeneous lateral organization of its molecular constituents. The heterogeneity may be sustained statically as well as dynamically. On the basis of recent experimental and theoretical progress in the study of the physical properties of lipid-bilayer membranes, it is proposed that the dynamically heterogeneous membrane states are important for membrane functions such as transport of matter across the membrane and enzymatic activity. The heterogeneous membrane states undergo significant structural changes in response to changes in compositional, thermodynamic, and environmental conditions. The diverse effects of a variety of molecular compounds interacting with membranes, such as cholesterol and drugs like anaesthetics, may be understood in terms of the ability of these compounds to affect and modulate the dynamic membrane heterogeneity.",
author = "Mouritsen, {Ole G.} and Kent J{\o}rgensen",
year = "1992",
doi = "10.1002/bies.950140211",
language = "English",
volume = "14",
pages = "129--136",
journal = "BioEssays",
issn = "0265-9247",
publisher = "Wiley",
number = "2",

}

RIS

TY - JOUR

T1 - Problems and paradigms: Dynamic lipid-bilayer heterogeneity

T2 - A mesoscopic vehicle for membrane function?

AU - Mouritsen, Ole G.

AU - Jørgensen, Kent

PY - 1992

Y1 - 1992

N2 - The lipid-bilayer component of cell membranes is an aqueous bimolecular aggregate characterized by a heterogeneous lateral organization of its molecular constituents. The heterogeneity may be sustained statically as well as dynamically. On the basis of recent experimental and theoretical progress in the study of the physical properties of lipid-bilayer membranes, it is proposed that the dynamically heterogeneous membrane states are important for membrane functions such as transport of matter across the membrane and enzymatic activity. The heterogeneous membrane states undergo significant structural changes in response to changes in compositional, thermodynamic, and environmental conditions. The diverse effects of a variety of molecular compounds interacting with membranes, such as cholesterol and drugs like anaesthetics, may be understood in terms of the ability of these compounds to affect and modulate the dynamic membrane heterogeneity.

AB - The lipid-bilayer component of cell membranes is an aqueous bimolecular aggregate characterized by a heterogeneous lateral organization of its molecular constituents. The heterogeneity may be sustained statically as well as dynamically. On the basis of recent experimental and theoretical progress in the study of the physical properties of lipid-bilayer membranes, it is proposed that the dynamically heterogeneous membrane states are important for membrane functions such as transport of matter across the membrane and enzymatic activity. The heterogeneous membrane states undergo significant structural changes in response to changes in compositional, thermodynamic, and environmental conditions. The diverse effects of a variety of molecular compounds interacting with membranes, such as cholesterol and drugs like anaesthetics, may be understood in terms of the ability of these compounds to affect and modulate the dynamic membrane heterogeneity.

U2 - 10.1002/bies.950140211

DO - 10.1002/bies.950140211

M3 - Journal article

C2 - 1575713

AN - SCOPUS:0026811372

VL - 14

SP - 129

EP - 136

JO - BioEssays

JF - BioEssays

SN - 0265-9247

IS - 2

ER -

ID: 236892038