Lipid rafts: At a crossroad between cell biology and physics

Research output: Contribution to journal › Review › Research › peer-review

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Lipid rafts : At a crossroad between cell biology and physics. / Jacobson, Ken; Mouritsen, Ole G.; Anderson, Richard G.W.

In: Nature Cell Biology, Vol. 9, No. 1, 01.01.2007, p. 7-14.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Jacobson, K, Mouritsen, OG & Anderson, RGW 2007, 'Lipid rafts: At a crossroad between cell biology and physics', Nature Cell Biology, vol. 9, no. 1, pp. 7-14. https://doi.org/10.1038/ncb0107-7

APA

Jacobson, K., Mouritsen, O. G., & Anderson, R. G. W. (2007). Lipid rafts: At a crossroad between cell biology and physics. Nature Cell Biology, 9(1), 7-14. https://doi.org/10.1038/ncb0107-7

Vancouver

Jacobson K, Mouritsen OG, Anderson RGW. Lipid rafts: At a crossroad between cell biology and physics. Nature Cell Biology. 2007 Jan 1;9(1):7-14. https://doi.org/10.1038/ncb0107-7

Author

Jacobson, Ken ; Mouritsen, Ole G. ; Anderson, Richard G.W. / Lipid rafts : At a crossroad between cell biology and physics. In: Nature Cell Biology. 2007 ; Vol. 9, No. 1. pp. 7-14.

Bibtex

@article{991ed1341cac4e558c3318c1814df1ff,
title = "Lipid rafts: At a crossroad between cell biology and physics",
abstract = "Membrane lateral heterogeneity is accepted as a requirement for the function of biological membranes and the notion of lipid rafts gives specificity to this broad concept. However, the lipid raft field is now at a technical impasse because the physical tools to study biological membranes as a liquid that is ordered in space and time are still being developed. This has lead to a disconnection between the concept of lipid rafts as derived from biochemical and biophysical assays and their existence in the cell. Here, we compare the concept of lipid rafts as it has emerged from the study of synthetic membranes with the reality of lateral heterogeneity in biological membranes. Further application of existing tools and the development of new tools are needed to understand the dynamic heterogeneity of biological membranes.",
author = "Ken Jacobson and Mouritsen, {Ole G.} and Anderson, {Richard G.W.}",
year = "2007",
month = jan,
day = "1",
doi = "10.1038/ncb0107-7",
language = "English",
volume = "9",
pages = "7--14",
journal = "Nature Cell Biology",
issn = "1465-7392",
publisher = "nature publishing group",
number = "1",

}

RIS

TY - JOUR

T1 - Lipid rafts

T2 - At a crossroad between cell biology and physics

AU - Jacobson, Ken

AU - Mouritsen, Ole G.

AU - Anderson, Richard G.W.

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Membrane lateral heterogeneity is accepted as a requirement for the function of biological membranes and the notion of lipid rafts gives specificity to this broad concept. However, the lipid raft field is now at a technical impasse because the physical tools to study biological membranes as a liquid that is ordered in space and time are still being developed. This has lead to a disconnection between the concept of lipid rafts as derived from biochemical and biophysical assays and their existence in the cell. Here, we compare the concept of lipid rafts as it has emerged from the study of synthetic membranes with the reality of lateral heterogeneity in biological membranes. Further application of existing tools and the development of new tools are needed to understand the dynamic heterogeneity of biological membranes.

AB - Membrane lateral heterogeneity is accepted as a requirement for the function of biological membranes and the notion of lipid rafts gives specificity to this broad concept. However, the lipid raft field is now at a technical impasse because the physical tools to study biological membranes as a liquid that is ordered in space and time are still being developed. This has lead to a disconnection between the concept of lipid rafts as derived from biochemical and biophysical assays and their existence in the cell. Here, we compare the concept of lipid rafts as it has emerged from the study of synthetic membranes with the reality of lateral heterogeneity in biological membranes. Further application of existing tools and the development of new tools are needed to understand the dynamic heterogeneity of biological membranes.

UR - http://www.scopus.com/inward/record.url?scp=33845901815&partnerID=8YFLogxK

U2 - 10.1038/ncb0107-7

DO - 10.1038/ncb0107-7

M3 - Review

C2 - 17199125

AN - SCOPUS:33845901815

VL - 9

SP - 7

EP - 14

JO - Nature Cell Biology

JF - Nature Cell Biology

SN - 1465-7392

IS - 1

ER -

ID: 230977607