Effect of high doses of L-ascorbic acid on the antioxidative/oxidative state in the rats

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Effect of high doses of L-ascorbic acid on the antioxidative/oxidative state in the rats. / Niemiec, T.; Sawosz, E.; Chwalibog, André.

In: Journal of Animal and Feed Sciences, Vol. 14, No. Suppl.1, 2005, p. 553-556.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Niemiec, T, Sawosz, E & Chwalibog, A 2005, 'Effect of high doses of L-ascorbic acid on the antioxidative/oxidative state in the rats', Journal of Animal and Feed Sciences, vol. 14, no. Suppl.1, pp. 553-556.

APA

Niemiec, T., Sawosz, E., & Chwalibog, A. (2005). Effect of high doses of L-ascorbic acid on the antioxidative/oxidative state in the rats. Journal of Animal and Feed Sciences, 14(Suppl.1), 553-556.

Vancouver

Niemiec T, Sawosz E, Chwalibog A. Effect of high doses of L-ascorbic acid on the antioxidative/oxidative state in the rats. Journal of Animal and Feed Sciences. 2005;14(Suppl.1):553-556.

Author

Niemiec, T. ; Sawosz, E. ; Chwalibog, André. / Effect of high doses of L-ascorbic acid on the antioxidative/oxidative state in the rats. In: Journal of Animal and Feed Sciences. 2005 ; Vol. 14, No. Suppl.1. pp. 553-556.

Bibtex

@article{010f0fe0a1c011ddb6ae000ea68e967b,
title = "Effect of high doses of L-ascorbic acid on the antioxidative/oxidative state in the rats",
abstract = "The objective of this study was to determine the effects of mega-doses of vitamin C (0.3, 0.6 and 0.9% of diet) as a dietary supplement for rats on selected indices of the antioxidative/oxidative state in 40 growing Wistar rats (4x10). It was found that L-ascorbic acid and Total Antioxidative State (TAS) in plasma did not increase with increasing vitamin C supply. The results indicate that high doses of L-ascorbic acid (0.3 and 0.9 but not 0.6%) increased the concentration of this antioxidant in plasma. Supplementation of vitamin C above 0.3% to the diets had pro-oxidative effects on lipid structures, while application of 0.9% promoted oxidative degradation of rat livers.",
keywords = "Former LIFE faculty, ascorbic acid, antioxidative/oxidative state, rats",
author = "T. Niemiec and E. Sawosz and Andr{\'e} Chwalibog",
year = "2005",
language = "English",
volume = "14",
pages = "553--556",
journal = "Journal of Animal and Feed Sciences",
issn = "1230-1388",
publisher = "Polska Akademia Nauk Instytut Fizjologii i Zywienia Zwierzat im. Jana Kielanowskiego",
number = "Suppl.1",

}

RIS

TY - JOUR

T1 - Effect of high doses of L-ascorbic acid on the antioxidative/oxidative state in the rats

AU - Niemiec, T.

AU - Sawosz, E.

AU - Chwalibog, André

PY - 2005

Y1 - 2005

N2 - The objective of this study was to determine the effects of mega-doses of vitamin C (0.3, 0.6 and 0.9% of diet) as a dietary supplement for rats on selected indices of the antioxidative/oxidative state in 40 growing Wistar rats (4x10). It was found that L-ascorbic acid and Total Antioxidative State (TAS) in plasma did not increase with increasing vitamin C supply. The results indicate that high doses of L-ascorbic acid (0.3 and 0.9 but not 0.6%) increased the concentration of this antioxidant in plasma. Supplementation of vitamin C above 0.3% to the diets had pro-oxidative effects on lipid structures, while application of 0.9% promoted oxidative degradation of rat livers.

AB - The objective of this study was to determine the effects of mega-doses of vitamin C (0.3, 0.6 and 0.9% of diet) as a dietary supplement for rats on selected indices of the antioxidative/oxidative state in 40 growing Wistar rats (4x10). It was found that L-ascorbic acid and Total Antioxidative State (TAS) in plasma did not increase with increasing vitamin C supply. The results indicate that high doses of L-ascorbic acid (0.3 and 0.9 but not 0.6%) increased the concentration of this antioxidant in plasma. Supplementation of vitamin C above 0.3% to the diets had pro-oxidative effects on lipid structures, while application of 0.9% promoted oxidative degradation of rat livers.

KW - Former LIFE faculty

KW - ascorbic acid

KW - antioxidative/oxidative state

KW - rats

M3 - Journal article

VL - 14

SP - 553

EP - 556

JO - Journal of Animal and Feed Sciences

JF - Journal of Animal and Feed Sciences

SN - 1230-1388

IS - Suppl.1

ER -

ID: 8000569