In situ atomic force microscope imaging of supported lipid bilayers
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
In situ AFM images of phospholipase A2 (PLA2) hydrolysis of mica-supported one- and two-component lipid bilayers are presented. For one-component DPPC bilayers an enhanced enzymatic activity is observed towards preexisting defects in the bilayer. Phase separation is observed in two-component DMPC-DSPC bilayers and a remarkable enhanced hydrolytic activity of the PLA2-enzyme for the DMPC-rich phase is seen. Furthermore, in a supported double bilayer system a characteristic ripple structure, most likely related to the formation of the Pβ'-ripple phase is observed.
Originalsprog | Engelsk |
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Tidsskrift | Single Molecules |
Vol/bind | 2 |
Udgave nummer | 2 |
Sider (fra-til) | 105-108 |
Antal sider | 4 |
ISSN | 1438-5163 |
DOI | |
Status | Udgivet - 1 jan. 2001 |
ID: 236896940