Research areas

  1. Published

    An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes

    Crielaard, B. J., Yousefi, A., Schillemans, J. P., Vermehren, C., Buyens, K., Braeckmans, K., Lammers, T. & Storm, G., Dec 2011, In : Journal of Controlled Release. 156, 3, p. 307-314

    Research output: Contribution to journalJournal article

  2. Published
  3. Published

    Computeren forudsiger lægemidlers omdannelse i leveren

    Rydberg, P. & Olsen, L., Dec 2011, In : Lægemiddelforskning. 2011, p. 44-46

    Research output: Contribution to journalJournal article

  4. Published

    Funktionelle fibriller som depotmedicin mod prostatakræft

    Jensen, M. G., van Maarschalkerweerd, A. & Gottschalk, T., Dec 2011, In : Lægemiddelforskning. 2011, p. 20-22

    Research output: Contribution to journalJournal article

  5. Published

    Gendannelse af ødelagt væv med stamceller

    Møller, E. H., Wen, Y. & Nielsen, Hanne Mørck, Dec 2011, In : Lægemiddelforskning. 2011, p. 13-15

    Research output: Contribution to journalJournal article

  6. Published

    Genetisk nanomedicin til behandling af leddegigt

    Foged, Camilla, Jensen, L. B. & Nielsen, Hanne Mørck, Dec 2011, In : Lægemiddelforskning. p. 7-9

    Research output: Contribution to journalJournal article

  7. Published

    Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv

    Janfelt, Christian, Thunig, J., Li, B., Andersen, N. W., Hansen, Harald S. & Hansen, S. H., Dec 2011, In : Lægemiddelforskning. 2011, p. 10-12

    Research output: Contribution to journalJournal article

  8. Published

    Medicinalplanter og abort: ny viden kan hjælpe afrikanske kvinder

    Jäger, A., Kristiansen, Uffe & Rasch, V., Dec 2011, In : Lægemiddelforskning. 2011, p. 23-25

    Research output: Contribution to journalJournal article

  9. Published

    Målrettet fisketur i hjernen giver ny viden om Fantasys virkningssted

    Villumsen, I. S., Vogensen, S. B., Frølund, Bente, Clausen, Rasmus Prætorius & Wellendorph, Petrine, Dec 2011, In : Lægemiddelforskning. 2011, p. 26-28

    Research output: Contribution to journalJournal article

  10. Published

    Nanobodies fra kameler - En ny klasse antistoffer til diagnostik og behandling

    Skottrup, P. D., Clausen, Rasmus Prætorius & Riise, E., Dec 2011, In : Lægemiddelforskning. 2011, p. 4-6

    Research output: Contribution to journalJournal article

  11. Published

    From retrospective assessment to prospective decisions in natural product isolation: HPLC-SPE-NMR analysis of Carthamus oxyacantha

    Kongstad, Kenneth Thermann, Wubshet, S. G., Nyberg, N. T. & Jaroszewski, J. W., 28 Nov 2011, In : Journal of Natural Products. 74, 11, p. 2454-2461

    Research output: Contribution to journalJournal article

  12. Published

    Small molecules from spiders used as chemical probes

    Olsen, C. A., Kristensen, Anders Skov & Strømgaard, Kristian, 25 Nov 2011, In : Angewandte Chemie International Edition. 50, 48, p. 11296-11311

    Research output: Contribution to journalReview

  13. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor

    Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Thomsen, A. R. B., Phonekeo, K., Pedersen, D. S. & Bräuner-Osborne, Hans, 23 Nov 2011, In : Chemistry & Biology. 18, 11, p. 1489-1498

    Research output: Contribution to journalJournal article

  14. Published

    Amino triazolo diazepines (Ata) as constrained histidine mimics

    Buysse, K., Farard, J., Nikolaou, A., Vanderheyden, P., Vauquelin, G., Pedersen, D. S., Tourwé, D. & Ballet, S., 16 Nov 2011, In : Organic Letters. 13, 24, p. 6468-6471

    Research output: Contribution to journalLetter

  15. Published

    Scientific social responsibility: a call to arms

    Krogsgaard-Larsen, Povl, Thostrup, P. & Besenbacher, F., 11 Nov 2011, In : Angewandte Chemie International Edition. 50, 46, p. 10738-10740

    Research output: Contribution to journalComment/debate

  16. Published

    Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO2

    Mikkelsen, L., Sheykhzade, Majid, Jensen, K. A., Saber, A. T., Jacobsen, N. R., Vogel, U. B., Wallin, H., Loft, Steffen & Møller, Peter, 10 Nov 2011, In : Particle and Fibre Toxicology. 8, 1, p. 32

    Research output: Contribution to journalJournal article

  17. Published

    Alleviation of nociception in rats by treatment with ceftriaxone, a ß-lactam that promote the expression of the excitatory amino acid transporter 2

    Bjerrum, Ole Jannik, Abrahamsen, B. & Honoré, P. G. H., Nov 2011.

    Research output: Contribution to conferencePosterCommunication

  18. Published

    Pharmacological and physiological studies of the calcium-sensing receptor

    Thomsen, A. R. B., Nov 2011, København: Det Farmaceutiske Fakultet. 89 p.

    Research output: Book/ReportPh.D. thesisResearch

  19. Published

    SDF2XYZ2SDF: how to exploit TINKER power in cheminformatics projects

    Tosco, P., Balle, T. & Shiri, F., Nov 2011, In : Journal of Molecular Modeling. 17, 11, p. 3021-3023

    Research output: Contribution to journalJournal article

  20. Published

    Antimicrobial evaluation of Huilliche plant medicine used to treat wounds

    Mølgaard, Per, Holler, J. G., Asar, B., Liberna, I., Rosenbæk, L. B., Jebjerg, C. P., Jørgensen, L., Lauritzen, J., Guzman, A., Adsersen, A. & Simonsen, H. T., 31 Oct 2011, In : Journal of Ethnopharmacology. 138, 1, p. 219-227

    Research output: Contribution to journalJournal article

  21. Published

    A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: Synthesis, resolution, pharmacology, and crystal structure

    Szymanska, E., Frydenvang, Karla Andrea, Contreras-Sanz, A., Pickering, Darryl S, Frola, E., Serafimoska, Z., Nielsen, Birgitte, Kastrup, Jette Sandholm Jensen & Johansen, Tommy Nørskov, 4 Oct 2011, In : Journal of Medicinal Chemistry. 54, 20, p. 7289-7298

    Research output: Contribution to journalJournal article

  22. Published

    Antifungal metabolites from fungal endophytes of Pinus strobus

    Sumarah, M. W., Kesting, J. R., Sørensen, D. & Miller, J. D., 1 Oct 2011, In : Phytochemistry. 72, 14-15, p. 1833-1837

    Research output: Contribution to journalJournal article

  23. Published

    Stress and medicine use for headache: does sense of coherence modify the association?

    Koushede, V. J., Holstein, B. E., Andersen, A. & Hansen, E. H., 1 Oct 2011, In : European Journal of Public Health. 21, 5, p. 656-61 6 p.

    Research output: Contribution to journalJournal article

  24. Published
  25. Published

    The calcium-sensing receptor and calcimimetics in blood pressure modulation

    Smajilovic, S., Yano, S., Jabbari, R. & Tfelt-Hansen, J., Oct 2011, In : British Journal of Pharmacology. 164, 3, p. 884-893

    Research output: Contribution to journalReview

  26. Published

    Metabolic profiling based on two-dimensional J-resolved 1H NMR data and parallel factor analysis

    Yilmaz, A., Nyberg, N. T. & Jaroszewski, J. W., 27 Sep 2011, In : Analytical Chemistry. 83, 21, p. 8278-8285

    Research output: Contribution to journalJournal article

  27. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study

    Kesting, J. R., Olsen, L., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 26 Sep 2011, In : Journal of Natural Products. 74, 10, p. 2206-2215

    Research output: Contribution to journalJournal article

  28. Published

    A highly selective agonist for the metabotropic glutamate receptor mGluR2

    Nielsen, S. D., Fulco, M., Serpi, M., Nielsen, Birgitte, Hansen, M. B., Hansen, K. L., Thomsen, C., Brodbeck, R., Bräuner-Osborne, Hans, Pellicciari, R., Norrby, P., Greenwood, J. R. & Clausen, Rasmus Prætorius, 23 Sep 2011, In : MedChemComm. 2, 11, p. 1120-1124

    Research output: Contribution to journalJournal article

  29. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, Brian, Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, Paul, Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal article

  30. Published

    Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats

    Stefkov, G., Kulevanova, S., Miova, B., Dinevska-Kjovkarovska, S., Mølgaard, Per, Jäger, A. K. & Josefsen, K., 1 Sep 2011, In : Pharmaceutical Biology. 49, 9, p. 885-892

    Research output: Contribution to journalJournal article

  31. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

    Dadsetan, S., Bak, Lasse Kristoffer, Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Leke, R., Schousboe, Arne & Waagepetersen, Helle S., 1 Sep 2011, In : Neurochemistry International. 59, 4, p. 482-8 7 p.

    Research output: Contribution to journalJournal article

  32. Published

    Ubiquitous plant compounds disturb cell-based assays

    Saaby, L. & Jäger, A. K., 1 Sep 2011, In : Journal of Ethnopharmacology. 137, 1, p. 942-943

    Research output: Contribution to journalComment/debate

  33. Published

    Acute but not delayed amphetamine treatment improves behavioral outcome in a rat embolic stroke model

    Rasmussen, Rune Skovgaard, Overgaard, K., Kristiansen, Uffe & Johansen, Flemming Fryd, Sep 2011, In : Neurological Research. 33, 7, p. 774-782 14 p.

    Research output: Contribution to journalJournal article

  34. Published

    Do two different reaction mechanisms contribute to the hydroxylation of primary amines by cytochrome P450?

    Rydberg, P. & Olsen, L., Sep 2011, In : Journal of Chemical Theory and Computation. 7, 10, p. 3399-3404

    Research output: Contribution to journalJournal article

  35. Published

    Evolution and applications of plant pathway resources and databases

    Sucaet, Y. & Deva, T., Sep 2011, In : Briefings in Bioinformatics. 12, 5, p. 530-544

    Research output: Contribution to journalJournal article

  36. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice

    Richner, M., Bjerrum, Ole Jannik, Nykjær, A. & Vaegter, C. B., 18 Aug 2011, In : Journal of Visualized Experiments. 54, p. e3092

    Research output: Contribution to journalJournal article

  37. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Buhl, M., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Møller, N. & Sørensen, M., 1 Aug 2011, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 2, p. G269-77

    Research output: Contribution to journalJournal article

  38. Published

    Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression: comparison with sertraline

    Andreasen T., Jesper, Henningsen, K., Bate, S., Christiansen, S. & Wiborg, O., 1 Aug 2011, In : Journal of Psychopharmacology. 25, 8, p. 1134-41 8 p.

    Research output: Contribution to journalJournal article

  39. Published

    ß-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons

    Lund, Trine Meldgaard, Obel, L. F., Risa, Ø. & Sonnewald, U., 1 Aug 2011, In : Neurochemistry International. 59, 2, p. 309-18 10 p.

    Research output: Contribution to journalJournal article

  40. Published

    Extraction and detection of Ionophores in the Aquatic Environment

    Bak, S. A., Hansen, M., Krogh, K. A., Björklund, E. & Halling-Sørensen, B., Aug 2011.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  41. Published

    Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging

    Østergaard, Jesper, Ye, F., Rantanen, Jukka, Yaghmur, Anan, Larsen, Susan Weng, Larsen, C. S. & Jensen, Henrik, Aug 2011, In : Journal of Pharmaceutical Sciences. 100, 8, p. 3405-3410

    Research output: Contribution to journalJournal article

  42. Published

    The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1

    Thorn, K., Nielsen, C. U., Jakobsen, P., Steffansen, B., Zercher, C. K. & Begtrup, M., Aug 2011, In : Bioorganic & Medicinal Chemistry Letters. 21, 15, p. 4597-4601

    Research output: Contribution to journalJournal article

  43. Published

    Open3DALIGN: an open-source software aimed at unsupervised ligand alignment

    Tosco, P., Balle, T. & Shiri, F., 27 Jul 2011, In : Journal of Computer - Aided Molecular Design. 25, 8, p. 777-783

    Research output: Contribution to journalJournal article

  44. Published

    Unraveling the high- and low-sensitivity agonist responses of nicotinic acetylcholine receptors

    Harpsøe, Kasper, Ahring, P. K., Christensen, J. K., Jensen, M. L., Peters, D. & Balle, T., 27 Jul 2011, In : Journal of Neuroscience. 31, 30, p. 10759-10766

    Research output: Contribution to journalJournal article

  45. Published

    RS-predictor: a new tool for predicting sites of cytochrome P450-mediated metabolism applied to CYP 3A4

    Zaretzki, J., Bergeron, C., Rydberg, P., Huang, T., Bennett, K. P. & Breneman, C. M., 25 Jul 2011, In : Journal of Chemical Information and Modeling. 51, 7, p. 1667-1689

    Research output: Contribution to journalJournal article

  46. Published

    Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines

    Nielsen, S. D., Smith, G. P., Begtrup, M. & Kristensen, Jesper Langgaard, 22 Jul 2011, In : Tetrahedron. 67, 29, p. 5261-5267

    Research output: Contribution to journalJournal article

  47. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

    Andersen, J., Stuhr-Hansen, N., Dorvil, Linda Grønborg, Toubro, S., Hansen, S. M. R., Eildal, J. N. N., Bond, A. D., Bøgesø, K. P., Bang-Andersen, B., Kristensen, Anders Skov & Strømgaard, Kristian, 19 Jul 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 29, p. 12137-12142

    Research output: Contribution to journalJournal article

  48. Published

    Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol

    Madsen, K. K., Ebert, B., Clausen, Rasmus Prætorius, Krogsgaard-Larsen, Povl, Schousboe, Arne & White, H. S., 1 Jul 2011, In : Journal of Pharmacology and Experimental Therapeutics. 338, 1, p. 214-219

    Research output: Contribution to journalJournal article

  49. Temocene: the porphycene analogue of temoporfin (Foscan®)

    Garcia-Diaz, M., Sanchez-Garcia, D., Nonell, S., Soriano, J., Villanueva, A., Stockert, J. C., Canete, M., Sagrista, M. L. & Mora, M., 1 Jul 2011, In : MedChemComm. 2, 7, p. 616-619 4 p.

    Research output: Contribution to journalJournal article

  50. Published

    Chemical composition and biological screening of Capsella bursa-pastoris

    Grosso, C., Vinholes, J., Silva, L. R., Guedes de Pinho, P., Goncalves, R. F., Valentao, P., Jäger, A. K. & Andrade, P. B., Jul 2011, In : Revista Brasileira de Farmacognosia. 21, 4, p. 635-644

    Research output: Contribution to journalJournal article

  51. Published

    Direct on-line monitoring of methylseleninic acid metabolism in hepatocytes using membrane inlet mass spectrometry

    Bak, S. A., Hansen, H. R., Badolo, L. & Lauritsen, F. R., Jul 2011.

    Research output: Contribution to conferencePosterResearch

  52. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

    Kristensen, J. B. L., Nielsen, A. L., Jørgensen, L., Kristensen, L. H., Helgstrand, C., Juknaite, L., Kristensen, Jesper Langgaard, Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius, Olsen, L. & Gajhede, Michael, 23 Jun 2011, In : F E B S Letters. 585, 12, p. 1951-1956

    Research output: Contribution to journalJournal article

  53. Published

    Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains

    Hein-Kristensen, L., Knapp, K. M., Franzyk, Henrik & Gram, L., 22 Jun 2011, In : B M C Microbiology. 11, 1, p. 144

    Research output: Contribution to journalJournal article

  54. Published

    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

    Lehre, A. C., Rowley, N. M., Zhou, Y., Holmseth, S., Guo, C., Holen, T., Hua, R., Laake, P., Olofsson, A. M., Poblete-Naredo, I., Rusakov, D. A., Madsen, K. K., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Danbolt, N. C., 1 Jun 2011, In : Epilepsy Research. 95, 1-2, p. 70-81

    Research output: Contribution to journalJournal article

  55. Published

    Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating

    Kristensen, Anders Skov, Jenkins, M. A., Banke, T. G., Schousboe, Arne, Makino, Y., Johnson, R. C., Huganir, R. & Traynelis, S. F., 1 Jun 2011, In : Nature Neuroscience. 14, 6, p. 727-735

    Research output: Contribution to journalJournal article

  56. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

    Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In : Journal of Neurochemistry. 117, 5, p. 824-32 9 p.

    Research output: Contribution to journalJournal article

  57. Published

    In silico predictions of hERG channel blockers in drug discovery: from ligand-based and target-based approaches to systems chemical biology

    Taboureau, O. & Jørgensen, Flemming Steen, Jun 2011, In : Combinatorial Chemistry & High Throughput Screening. 14, 5, p. 375-387

    Research output: Contribution to journalJournal article

  58. Published

    Epitope grafting, re-creating a conformational Bet v 1 antibody epitope on the surface of the homologous apple allergen Mal d 1

    Holm, J., Ferreras, M., Ipsen, H., Würtzen, P. A., Gajhede, Michael, Larsen, J. N., Lund, K. & Spangfort, M. D., 20 May 2011, In : Journal of Biological Chemistry. 286, 20, p. 17569-17578

    Research output: Contribution to journalJournal article

  59. Published

    Expression and beta-glucan binding properties of Scots pine (Pinus sylvestris L.) antimicrobial protein (Sp-AMP)

    Sooriyaarachchi, S., Jaber, E., Covarrubias, A. S., Ubhayasekera, W., Asiegbu, F. O. & Mowbray, S. L., 17 May 2011, In : Plant Molecular Biology. 77, 1-2, p. 33-45

    Research output: Contribution to journalJournal article

  60. Published

    Extraction and detection of Ionophores in the Aquatic Environment

    Bak, S. A., Hansen, M., Krogh, K. A., Björklund, E. & Halling-Sørensen, B., 17 May 2011.

    Research output: Contribution to conferencePosterResearch

  61. Published

    Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2 -isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors

    Dallanoce, C., Magrone, P., Matera, C., Frigerio, F., Grazioso, G., De Amici, M., Fucile, S., Piccari, V., Frydenvang, Karla Andrea, Pucci, L., Gotti, C., Clementi, F. & De Micheli, C., 2 May 2011, In : ChemMedChem. 6, 5, p. 889-903

    Research output: Contribution to journalJournal article

  62. Published

    Thapsigargin affinity purification of intracellular P2A-type Ca2+ ATPases

    Vandecaetsbeek, I., Christensen, Søren Brøgger, Liu, H., van Veldhoven, P. P., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P., 1 May 2011, In : BBA General Subjects. 1813, 5, p. 1118-1127

    Research output: Contribution to journalJournal article

  63. Published

    1,2,3-triazoles in peptidomimetic chemistry

    Pedersen, D. S. & Abell, A., May 2011, In : European Journal of Organic Chemistry. 2011, 13, p. 2399-2411

    Research output: Contribution to journalReview

  64. Published

    New insights into the GABAA receptor structure and orthosteric ligand binding: Receptor modeling guided by experimental data

    Sander, T., Frølund, Bente, Bruun, A. T., Ivanov, I., McCammon, J. A. & Balle, T., May 2011, In : Proteins: Structure, Function, and Bioinformatics. 79, 5, p. 1458-1477

    Research output: Contribution to journalJournal article

  65. Published

    Studies of monoamine transporters: Phosphorylation of the serotonin transporter and interactions of antidepressants with the serotonin and norepinephrine transporters

    Sørensen, L., May 2011, København: Det Farmaceutiske Fakultet. 174 p.

    Research output: Book/ReportPh.D. thesisResearch

  66. Published

    X-ray crystal structure and small-angle X-ray scattering of sheep liver sorbitol dehydrogenase

    Yennawar, H., Møller, M., Gillilan, R. & Yennawar, N., May 2011, In : Acta Crystallographica. Section D: Biological Crystallography. 67, Pt 5, p. 440-446

    Research output: Contribution to journalJournal article

  67. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, Ole Jannik, Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 Apr 2011, In : European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.

    Research output: Contribution to journalJournal article

  68. Published

    Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain)

    López, V., Jäger, A. K., Akerreta, S., Cavero, R. Y. & Calvo, M. I., 12 Apr 2011, In : Journal of Ethnopharmacology. 134, 3, p. 1014-1017

    Research output: Contribution to journalJournal article

  69. Published

    Electrophilic organic selenium reagents: protonated seleninic acids as precursors for unsymmetrical aromatic selenides

    Stuhr-Hansen, N., Sølling, Theis Ivan & Henriksen, L., 8 Apr 2011, In : Tetrahedron. 67, 14, p. 2633-2643

    Research output: Contribution to journalJournal article

  70. Published

    ZP2307, a novel cyclic PTH(1-17) analog, reversed established osteopenia in adult ovariectomized rats

    Vääräniemi, J., Morko, J., Peng, Z., Rissanen, J. P., Suominen, M. I., Fagerlund, K. M., Suutari, T. A., Boonen, Harrie C.M., Neerup, T. S., Bak, H. H. & Halleen, J. M., 7 Apr 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  71. Published

    Discovery of benzamide analogues as a novel class of 5-HT3 receptor agonists

    Jørgensen, C. G., Frølund, Bente, Kehler, J. & Jensen, Anders A., 4 Apr 2011, In : ChemMedChem. 6, 4, p. 725-736

    Research output: Contribution to journalJournal article

  72. Published

    Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity

    Søvsø Jensen, B., Christensen, Søren Brøgger, Jäger, A. K. & Rønsted, Nina, Apr 2011, In : Biochemical Systematics and Ecology. 39, 2, p. 153-155

    Research output: Contribution to journalJournal article

  73. Published

    Glutamate receptor agonists: stereochemical aspects

    Vogensen, S. B., Greenwood, J. R., Bunch, Lennart & Clausen, Rasmus Prætorius, Apr 2011, In : Current Topics in Medicinal Chemistry. 11, 7, p. 887-906

    Research output: Contribution to journalReview

  74. Published

    Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction

    Bach, Anders, Eildal, J. N. N., Stuhr-Hansen, N., Deeskamp, R., Gottschalk, M., Pedersen, S. W., Kristensen, Anders Skov & Strømgaard, Kristian, 10 Mar 2011, In : Journal of Medicinal Chemistry. 54, 5, p. 1333-1346

    Research output: Contribution to journalJournal article

  75. Published

    European new safe and innovative medicines initiatives: history and progress (through December 2009)

    Bjerrum, Ole Jannik & H. Linden, H., Mar 2011, Translational medicine and drug discovery. Cambridge: Cambridge University Press, p. 265-288 23 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  76. Published

    Metabolic profiling of Rhodiola rosea rhizomes by 1H NMR spectroscopy

    Ioset, K. N., Nyberg, N. T., Van Diermen, D., Malnoe, P., Hostettmann, K., Shikov, A. N. & Jaroszewski, J. W., Mar 2011, In : Phytochemical Analysis. 22, 2, p. 158-165

    Research output: Contribution to journalJournal article

  77. Published

    G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations

    Ísberg, V., Balle, T., Sander, T., Jørgensen, Flemming Steen & Gloriam, David E., 28 Feb 2011, In : Journal of Chemical Information and Modeling. 51, 2, p. 315-325

    Research output: Contribution to journalJournal article

  78. Published

    Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp

    Runager, K., Basaiawmoit, R. V., Deva, T., Andreasen, M., Valnickova, Z., Sørensen, C. S., Karring, H., Thøgersen, I. B., Christiansen, G., Underhaug, J., Kristensen, T., Nielsen, N. C., Klintworth, G. K., Otzen, D. E. & Enghild, J. J., 18 Feb 2011, In : The Journal of Biological Chemistry. 286, 7, p. 4951-4958

    Research output: Contribution to journalJournal article

  79. Published

    Medicinal chemistry of competitive kainate receptor antagonists

    Larsen, A. M. & Bunch, Lennart, 16 Feb 2011, In : ACS Chemical Neuroscience. 2, 2, p. 60-74

    Research output: Contribution to journalReview

  80. Published

    Flavonoids and the CNS

    Jäger, A. K. & Saaby, L., 10 Feb 2011, In : Molecules. 16, 2, p. 1471-1485

    Research output: Contribution to journalReview

  81. Published

    Functional and structural studies of neuronal D-serine transporter Asc1

    Wang, X., 10 Feb 2011, København: Det Farmaceutiske Fakultet. 148 p.

    Research output: Book/ReportPh.D. thesisResearch

  82. Published

    Expedient synthesis of 1,3-substituted benzene peptidomimetics

    Bach, Anders & Strømgaard, Kristian, 8 Feb 2011, In : Synthesis. 2011, 5, p. 807-815

    Research output: Contribution to journalJournal article

  83. Published

    Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97

    Chi, C. N., Bach, Anders, Engström, Å., Strømgaard, Kristian, Lundström, P., Ferguson, N. & Jemth, P., 4 Feb 2011, In : Journal of Biological Chemistry. 286, 5, p. 3597-3606

    Research output: Contribution to journalJournal article

  84. Published

    Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

    Pinto, A., Conti, P., Grazioso, G., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte & De Micheli, C., 1 Feb 2011, In : European Journal of Medicinal Chemistry. 46, 2, p. 787-793

    Research output: Contribution to journalJournal article

  85. Published
  86. Published

    Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.)

    Saaby, L., Jäger, A. K., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Feb 2011, In : Phytotherapy Research. 25, 2, p. 195-201

    Research output: Contribution to journalJournal article

  87. Published

    The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load

    Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Å., Sandbaek, A., Lauritzen, T., Pisinger, Charlotta Holm, Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In : BMC Medical Genetics. 12, 1, p. 4 8 p.

    Research output: Contribution to journalJournal article

  88. Published
  89. Published

    Potentiating action of propofol at GABAA receptors of retinal bipolar cells

    Yue, L., Xie, A., Bruzik, K. S., Frølund, Bente, Qian, H. & Pepperberg, D. R., 1 Jan 2011, In : Investigative Ophthalmology & Visual Science. 52, 5, p. 2497-2509

    Research output: Contribution to journalJournal article

  90. Published

    Purification, crystallization and preliminary X-ray diffraction of the G3BP1 NTF2-like domain

    Vognsen, T., Möller, Ingvar Rúnar & Kristensen, O., 1 Jan 2011, In : Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 67, Pt 1, p. 48-50

    Research output: Contribution to journalJournal article

  91. Published

    Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA(A) receptors

    Nilsson, J., Gidlöf, R., Nielsen, E. Ø., Liljefors, T., Nielsen, M. P. C. & Sterner, O., 1 Jan 2011, In : Bioorganic & Medicinal Chemistry. 19, 1, p. 111-121

    Research output: Contribution to journalJournal article

  92. Published

    Effects of bile on the oral absorption of poorly water-soluble drugs in rats

    Tønsberg, H., Jan 2011, København: Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet. 83 p.

    Research output: Book/ReportPh.D. thesisResearch

  93. Published

    On-chip electro membrane extraction with online ultaviolet and mass spectrometric detection

    Petersen, Nickolaj J., Foss, S. T., Jensen, H., Hansen, S. H., Skonberg, C., Snakenborg, D., Kutter, J. P. & Pedersen-Bjergaard, Stig, Jan 2011, In : Analytical Chemistry. 83, 1, p. 44-51

    Research output: Contribution to journalJournal article

  94. Published

    (Eco)teoxicological effects of transformation products: (Not) a research question ?

    Hansen, M., 2011.

    Research output: Working paperResearch

  95. Published

    1H NMR- and HPLC-based metabolomics combined with hyphenated HPLC-SPE-NMR methods for the investigation of herbal remedies and medicinal plants

    Agnolet, Sara, 2011, København: Det Farmaceutiske Fakultet.

    Research output: Book/ReportPh.D. thesisResearch

  96. Published

    2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

    Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17

    Research output: Contribution to journalJournal article

  97. Published

    In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin

    Jensen, L. B., Petersson, K. & Nielsen, Hanne Mørck, 2011, In : European Journal of Pharmaceutics and Biopharmaceutics. 79, 1, p. 68-75

    Research output: Contribution to journalJournal article

  98. Published

    A ligand's view of target similarity: chemogenomic binding site-directed techniques for drug discovery

    Garland, S. L. & Gloriam, David E., 2011, In : Current Topics in Medicinal Chemistry. 11, 15, p. 1872-1881

    Research output: Contribution to journalJournal article

  99. Published

    A model on the carbon cycling in Lake Taihu, China

    Weiping, H., Jørgensen, S. E., Fabing, Z., Yonggen, C., Zhixin, H. & Longyuan, Y., 2011, In : Ecological Modelling. 222, 16, p. 2973-2991

    Research output: Contribution to journalJournal article

  100. Published

    A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

    Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In : European Journal of Pharmaceutical Sciences. 42, p. 416-422

    Research output: Contribution to journalJournal article

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