Research areas

  1. Published

    Impact of carriers in oral absorption: permaeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide

    Gram, L. K., Rist, G. M., Lennernäs, H. & Steffansen, B., 2009, In: European Journal of Pharmaceutical Sciences. 37, p. 378-386

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Molekylær biofarmaci - når medicinen skyder genvej!

    Gram, L. K., Omkvist, D. H., Larsen, M., Nielsen, C. U., Larsen, Birger Brodin & Steffansen, I. D., 2007, In: Lægemiddelforskning. p. 16-17

    Research output: Contribution to journalJournal articleCommunication

  3. Published

    Inhibitors of the PSD-95/NMDA receptor interaction: development of a BRET assay and evaluation of binding sites

    Gottschalk, M., 2011, København: Det Farmaceutiske Fakultet. 142 p.

    Research output: Book/ReportPh.D. thesisResearch

  4. Published

    Brain activation due to postoperative pain from the right hand measured with regional cerebral blood flow using positron emission tomography

    Gordh, T., Vinnars, B., Blomberg, H., Modig, J., Frederikson, M. & Honoré, P. G. H., Jul 2010, In: Scandinavian Journal of Pain. 1, 3, p. 115-119 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Volatile organic compounds in landfill ordorant emissions on the island of Mallorca

    González, C. R., Björklund, E., Forteza, R. & Cerdà, V., 2012, In: International Journal of Environmental Analytical Chemistry. 92, 12, p. 1-16, iFirst

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design

    Gloriam, David E., Foord, S. M., Blaney, F. E. & Garland, S. L., 2009, In: Journal of Medicinal Chemistry. 52, 14, p. 4429-4442

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Kemogenomik: receptoren set fra lægemiddelstoffets synspunkt

    Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Pedersen, D. S. & Bräuner, Hans, Dec 2010, In: Lægemiddelforskning. 2010, p. 28-30

    Research output: Contribution to journalJournal articleCommunication

  8. Published

    A community standard format for the representation of protein affinity reagents

    Gloriam, D. E. I., Orchard, S., Bertinetti, D., Björling, E., Bongcam-Rudloff, E., Borrebaeck, C. A. K., Bourbeillon, J., Bradbury, A. R. M., de Daruvar, A., Dübel, S., Frank, R., Gibson, T. J., Gold, L., Haslam, N., Herberg, F. W., Hiltke, T., Hoheisel, J. D., Kerrien, S., Koegl, M., Konthur, Z. & 16 others, Korn, B., Landegren, U., Montecchi-Palazzi, L., Palcy, S., Rodriguez, H., Schweinsberg, S., Sievert, V., Stoevesandt, O., Taussig, M. J., Ueffing, M., Uhlén, M., van der Maarel, S., Wingren, C., Woollard, P., Sherman, D. J. & Hermjakob, H., 2010, In: Molecular and Cellular Proteomics. 9, 1, p. 1-10

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor

    Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Thomsen, A. R. B., Phonekeo, K., Pedersen, D. S. & Bräuner, Hans, 23 Nov 2011, In: Chemistry & Biology. 18, 11, p. 1489-1498

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Low-resolution structure of a vesicle disrupting a-synuclein oligomer that accumulates during fibrillation

    Giehm, L., Svergun, D. I., Otzen, D. E. & Vestergaard, Bente, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 8, p. 3246-3251

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Selective pressurized liquid extraction of three classes of halogenated contaminants in fish

    Ghosh, R., Hageman, K. J. & Björklund, E., 2011, In: Journal of Chromatography A. 11218, 41, p. 7242-7247

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Fishing for contaminants in McMurdo sound: Antarctica: Analytical methods

    Ghosh, R., Hageman, K., Björklund, B. E., Lamare, M., Metcalf, V. & Lokman, M., 2009.

    Research output: Contribution to conferencePosterCommissioned

  13. Published

    Ufølsomme hjerter i livsfare

    Ghorbani, M. L. M., Fjalland, B., Sheykhzade, Majid & Nyborg, N. C. B., 2008, In: Lægemiddelforskning. p. 49-51

    Research output: Contribution to journalJournal articleCommunication

  14. Published

    Characterization of upper thoracic spinal neurons receiving noxious cardiac and/or somatic inputs in diabetic rats

    Ghorbani, M. L. M., Qin, C., Wu, M., Farber, J. P., Sheykhzade, Majid, Fjalland, B., Nyborg, N. C. B. & Foreman, R. D., 7 Dec 2011, In: Autonomic Neuroscience: Basic and Clinical. 165, 2, p. 168-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A ligand's view of target similarity: chemogenomic binding site-directed techniques for drug discovery

    Garland, S. L. & Gloriam, David E., 2011, In: Current Topics in Medicinal Chemistry. 11, 15, p. 1872-1881

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Methods for the successful application of chemogenomics to GPCR drug design

    Garland, S. L. (ed.) & Gloriam, David E. (ed.), 2011, In: Current Topics in Medicinal Chemistry. 11, 15, p. 1870-1871

    Research output: Contribution to journalEditorialResearch

  17. Published

    Harp seal ageing techniques-teeth, aspartic acid racemization, and telomere sequence analysis

    Garde, E., Frie, A. K., Dunshea, G., Hansen, S. H., Kovas, K. M. & Lydersen, C., 2010, In: Journal of Mammalogy. 91, 6, p. 1365-1374

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Age-specific growth and remarkable longevity in narwhals (monodon monoceros) from West Greenland as estimated by aspartic acid racemization

    Garde, E., Heide-Jørgensen, M. P., Hansen, S. H., Nachman, Gøsta Støger & Forchhammer, M., 2007, In: Journal of Mammalogy. 88, 1, p. 49-58

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Temocene: the porphycene analogue of temoporfin (Foscan®)

    Garcia-Diaz, M., Sanchez-Garcia, D., Nonell, S., Soriano, J., Villanueva, A., Stockert, J. C., Canete, M., Sagrista, M. L. & Mora, M., 1 Jul 2011, In: MedChemComm. 2, 7, p. 616-619 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Impact of adult atopic dermatitis on topical drug penetration: assessment by cutaneous microdialysis and tape stripping

    Garcia Ortiz, P., Hansen, S. H., Shah, V. P., Menné, T. & Benfeldt, E., 2009, In: Acta Dermato Venereologica. 89, 1, p. 33-38 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The use of inductively coupled plasma mass spectrometry as a detector in drug metabolism studies

    Gammelgaard, Bente, Hansen, H. R., Stürup, Stefan & Møller, C., 2008, In: Expert Opinion on Drug Metabolism & Toxicology. 4, 9, p. 1187-1207

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Surveying selenium speciation from soil to cell-forms and transformations

    Gammelgaard, Bente, Jackson, M. I. & Gabel-Jensen, C., 2011, In: Analytical and Bioanalytical Chemistry. 399, p. 1743-1763

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Estimating intestinal absorption of inorganic selenium compounds by in vitro flux and biotransformation studies in Caco-2 cells and ICP-MS detection

    Gammelgaard, Bente, Rasmussen, L. H., Gabel-Jensen, C. & Steffansen, B., 2012, In: Biological Trace Element Research. 145, 2, p. 248-256

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Human urinary excretion and metabolism of 82Se-enriched selenite and selenate determined by LC-ICP-MS

    Gammelgaard, Bente, Stürup, Stefan & Christensen, M. V., 2012, In: Metallomics. 4, 2, p. 149-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    LC-ICP-MS and LC-ESI-(MS)n identification of Se-methylselenocysteine and selenomethionine as metabolites of methylseleninic acid in rat hepatocytes

    Gabel-Jensen, C., Jacobsen, J. O., Skonberg, C., Badolo, L. & Gammelgaard, Bente, 2009, In: Journal of Analytical Atomic Spectrometry. 24, p. 69-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Selenium metabolism in hepatocytes incubated with selenite, selenate, selenomethionie, Se-methylselenocysteine and  methylseleninc acid and analysed by LC-ICP-MS

    Gabel-Jensen, C. & Gammelgaard, Bente, 2010, In: Journal of Analytical Atomic Spectrometry. 25, p. 414-118

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Separation and identification of the selenium-sulfur amino acid S-(methylseleno)cysteine in intestinal epithelial cell homogenates by LC-ICP-MS and LC-ESI-MS after incubation with methylseleninic acid

    Gabel-Jensen, C., Lunøe, K., Madsen, K. G., Bendix, Jesper, Cornett, Claus, Stürup, Stefan, Hansen, H. R. & Gammelgaard, Bente, 2008, In: Journal of Analytical Atomic Spectrometry. 23, p. 727-732

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    In situ identification of dimethyl diselenide in hepatocytes treated with methylseleninic acid by membrane inlet mass spectrometry

    Gabel-Jensen, C., Bak, S. A., Lauritsen, F. R., Hansen, H. R., Badolo, L. & Gammelgaard, Bente, 2009, In: Journal of Analytical Atomic Spectrometry. 24, p. 949-952

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Formation of methylselenol, dimethylselenide and dimethyldiselenide in in vitro metabolism models determined by headspace GC-MS

    Gabel-Jensen, C., Lunøe, K. & Gammelgaard, Bente, 2010, In: Metallomics. 2, p. 167-173

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Impact of bias discrepancy and amino acid usage on estimates of the effective number of codons used in a gene, and a test for selection on codon usage

    Fuglsang, A., 2007, In: Gene. 410, 1, p. 82-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Preparation and in vitro evaluation of pH, time-based and enzyme-degradable pellets for colonic drug delivery

    Fude, C., Lei, Y., Lie, J., Hongze, P., Wenhui, L. & Cun, D., 2007, In: Drug Development and Industrial Pharmacy. 33, 9, p. 999-1007

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors

    Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.

    Research output: Contribution to conferencePosterResearch

  33. Published

    Gly-sar is a substrate for the human proton coupled amino acid trasporter 1, hPAT1 (SLC36A1)

    Frølund, S. B., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., 2010.

    Research output: Contribution to conferencePosterResearch

  34. Published

    d-Aminolevulinic acid is a substrate for the amino acid transporter SLC36A1 (hPAT1)

    Frølund, S., Marquez, O. C., Larsen, M., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: British Journal of Pharmacology. 159, 6, p. 1339-1353

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

    Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    GABA and glutamic acid receptor ligands

    Frølund, Bente & Madsen, Ulf, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 239-262

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  37. Published

    Ligands for the GABA recognition site at the GABAA receptor: Structure-activity studies

    Frølund, Bente, Kristiansen, Uffe, Krogsgaard-Larsen, Povl & Liljefors, T., 2008, Chemistry and molecular aspects of drug design and action. Rekka, E. A. & Kourounakis, P. N. (eds.). Boca Raton, Fl: CRC Press, p. 139-147

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  38. Published

    GABAA-receptoren: Bedre modeller - bedre lægemidler

    Frølund, Bente, Sander, T., Hansen, H. & Balle, T., 2009, In: Lægemiddelforskning. p. 31-33

    Research output: Contribution to journalJournal articleCommunication

  39. Published

    4-aryl-5-(4-piperidyl)-3-isoxazolol GABAA antagonists: synthesis, pharmacology, and structure-activity relationships

    Frølund, Bente, Jensen, L. S., Storustovu, S. I., Stensbøl, T. B., Ebert, B., Kehler, J., Krogsgaard-Larsen, Povl & Liljefors, T., 2007, In: Journal of Medicinal Chemistry. 50, 8, p. 1988-1992

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine

    Frydenvang, Karla Andrea, Lash, L. L., Naur, P., Postila, P. A., Pickering, Darryl S, Smith, C. M., Gajhede, Michael, Sasaki, M., Sakai, R., Pentikäinen, O. T., Swanson, G. T. & Kastrup, Jette Sandholm Jensen, 2009, In: Journal of Biological Chemistry. 284, 21, p. 14219-14229

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    At være eller ikke være en antagonist

    Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2009, In: Lægemiddelforskning. p. 43-45

    Research output: Contribution to journalJournal articleCommunication

  42. Published

    On the search for in vitro in vivo correlations in the field of intra-articular drug delivery: Administration of sodium diatrizoate to the horse

    Frost, A. B., Larsen, F., Østergaard, Jesper, Larsen, Susan Weng, Lindegaard, Casper, Hansen, H. R. & Larsen, C. S., 2010, In: European Journal of Pharmaceutical Sciences. 41, p. 10-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Nye depotlægemidler til injektion i gigtramte led: kan laboratoriemodeller reducere antallet af dyreforsøg

    Frost, A. B., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C. S., 2008, In: Lægemiddelforskning. p. 46-48

    Research output: Contribution to journalJournal articleCommunication

  44. Published

    The pharmacokinetics of the weakly protein-bound anionic compound diatrizoate in serum and synovial fluid of the horse

    Frost, A. B., Larsen, F., Larsen, Susan Weng, Østergaard, Jesper, Thomsen, M. H., Stürup, Stefan, Andersen, P. H. & Larsen, C. S., 2010, In: Pharmaceutical Research. 27, 1, p. 143-150 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    On the search for in vitro in vivo relations in the field of parenteral depot formulations intended for intra-articular injection

    Frost, A. B., 2011, København. 163 p.

    Research output: Book/ReportPh.D. thesisResearch

  46. Published

    Intra-articular injection of morphine to the horse: Establishment of an in vitro-in vivo relationship

    Frost, A. B., Lindegaard, Casper, Larsen, F., Østergaard, Jesper, Larsen, Susan Weng & Larsen, C. S., 2011, In: Drug Development and Industrial Pharmacy. 37, 9, p. 1043-1048

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Øvelsesvejledning til bioorganisk kemi: øvelser M23-2

    Franzyk, Henrik, 2007, Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

    Research output: Book/ReportCompendium/lecture notesEducation

  48. Published

    Noter til bioorganisk kemi M23-1

    Franzyk, Henrik, Christensen, Søren Brøgger & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

    Research output: Book/ReportCompendium/lecture notesEducation

  49. Published

    Liposomer i lægemiddelforskning

    Franzen, U., Jørgensen, Lene, Larsen, C. S., Jensen, H. & Østergaard, Jesper, 2007, In: Lægemiddelforskning. p. 14-15

    Research output: Contribution to journalJournal articleCommunication

  50. Published

    Physicochemical characterization of a PEGylated liposomal drug formulation using capillary electrophoresis

    Franzen, U., Vermehren, C., Jensen, H. & Østergaard, Jesper, 2011, In: Electrophoresis. 32, 6-7, p. 738-748

    Research output: Contribution to journalJournal articleResearchpeer-review