Research areas

  1. Published

    Low-level efficacy of cosmetic preservatives

    Lundov, M. D., Johansen, J. D., Zachariae, C. & Moesby, L., 2011, In: International Journal of Cosmetic Science. 33, 2, p. 190-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    COX-1 inhibition of Heteromorpha arborescens

    Lundgaard, N. H., Prior, R. M., Light, M. E., Stafford, G. I., van Staden, J. & Jäger, A. K., 2008, In: South African Journal of Botany. 74, 2, p. 335-337

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Aspartate-glutamate homeostasis in cerebellar neurons changes when shifting from glucose to beta-hydroxybutyrate as substrate

    Lund, Trine Meldgaard, Clausen, M., Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 291-291

    Research output: Contribution to journalConference abstract in journalResearch

  4. Published

    Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons

    Lund, Trine Meldgaard, Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 110, 1, p. 80-91 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    ß-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons

    Lund, Trine Meldgaard, Obel, L. F., Risa, Ø. & Sonnewald, U., 1 Aug 2011, In: Neurochemistry International. 59, 2, p. 309-18 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    ß-hydroxybutyrate and glucose metabolism is differently affected by neuronal activity

    Lund, Trine Meldgaard, Clausen, M., Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 116

    Research output: Contribution to journalConference abstract in journalResearch

  7. Published

    GABA synthesis from ß-hydroxybutyrate and glucose is differentially affected by neuronal activity in cultured GABAergic neurons

    Lund, Trine Meldgaard, Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s2, p. 95

    Research output: Contribution to journalConference abstract in journalResearch

  8. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Design, synthesis and structure-activity analysis of isoform-selective retinoic acid receptor beta ligands

    Lund, B. W., 2007, København: Det Farmaceutiske Fakultet. 197 p.

    Research output: Book/ReportPh.D. thesisResearch

  10. Published

    Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor ß ligands

    Lund, B. W., Knapp, A. E., Piu, F., Gauthier, N. K., Begtrup, M., Hacksell, U. & Olsson, R., 2009, In: Journal of Medicinal Chemistry. 52, 6, p. 1540-1545

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Lippia javanica (Burm F) Spreng: its general constituents and bioactivity on mosquitoes

    Lukwa, N., Mølgaard, Per, Furu, Peter & Bøgh, C., 2009, In: Tropical Biomedicine. 26, 1, p. 85-91

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound

    Lue, B., Nielsen, F. S., Magnussen, T., Schou, H. M., Kristensen, K., Jacobsen, L. O. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 69, 2, p. 648-657

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

    Lovatt, D., Sonnewald, U., Waagepetersen, Helle S., Schousboe, Arne, He, W., Lin, J. H., Han, X., Takano, T., Wang, S., Sim, F. J., Goldman, S. A. & Nedergaard, M., 2007, In: Journal of Neuroscience. 27, 45, p. 12255-12266

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    In vitro dissolution

    Lomstein Pedersen, B. & Müllertz, A., 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage from evaluation. Steffansen, B., Brodin, B. & Uhd Nielsen, C. (eds.). Pharmaceutical Press, p. 257-273

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  15. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, B., Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, P. A. C., Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In: Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    MCF-7 human mammary adenocarcinoma cells exhibit augmented responses to human insulin on a collagen IV surface

    Listov-Saabye, N., Jensen, M. B., Kiehr, B., Hansen, E. W., Svendsen, J. E., Lundby, A., Holm, G. N. & Oleksiewicz, M. B., 2009, In: Journal of Applied Toxicology. 29, 6, p. 470-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Do family practitioners in Lithuania inform their patients about adverse effects of common medications?

    Liseckiene, I., Liubarskiene, Z., Jacobsen, Ramune, Valius, L. & Norup, M. S., 2008, In: Journal of Medical Ethics. 34, 3, p. 137-140

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes

    Lindvall, T., Karlsson, J., Holmdahl, R. & Andersson, Åsa, 2009, In: Arthritis Research & Therapy. 11, 1, p. R10

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80

    Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutical Sciences. 35, 3, p. 211-218

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

    Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Knowledge creation processes in researceh and development: a case study in the pharmaceutical industry

    Lilleøre, A., 2010, København: Museum Tusculanum. 67 p.

    Research output: Book/ReportPh.D. thesisResearch

  22. Published

    Knowledge-sharing practices in pharmaceutical research and development—a case study.

    Lilleoere, A. & Hansen, E. H., 2011, In: Knowledge and Process Management (Print Edition). 18, 3, p. 121-132 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Molecular recognition in ligand-protein binding

    Liljefors, T., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 15-27

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  24. Published

    Increased litter size and super-ovulation rate in congenic C57BL mice carrying a polymorphic fragment of NFR/N origin at the Fecq4 locus of chromosome 9

    Liljander, M., Andersson, Åsa, Holmdahl, R. & Mattsson, R., 2009, In: Genetics Research. 91, 4, p. 259-65 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Increased susceptibility to collagen-induced arthritis in female mice carrying congenic Cia40/Pregq2 fragments

    Liljander, M., Andersson, Åsa, Holmdahl, R. & Mattsson, R., 2008, In: Arthritis Research & Therapy. 10, 4, p. R88 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Environmental risk assessment of ivermectin - A case study with a veterinary pharmaceutical

    Liebig, M., Fernandez, A. A., Blübaum-Gronau, E., Boxall, A., Duis, K., Egeler, P., Fenner, K., Fink, G., Garric, J., Halling-Sørensen, B., Jensen, J., Knacker, T., Krogh, K. A., Küster, A., Pope, L., Römbke, J., Rönnefahrt, I., Argüello, P. S., Schneider, M., Tait, A. & 3 others, Tarazona, J., Ternes, T. & Werhan, A., 2008, World under stress: scientific and applied issues in environmental toxicology and chemistry. Society of Environmental Toxicology and Chemistry, p. 28-28

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  27. Published

    Environmental risk assessment of ivermectin: A case study

    Liebig, M., Fernandez, Á. A., Blübaum-Gronau, E., Boxall, A., Brinke, M., Carbonell, G., Egeler, P., Fenner, K., Fernandez, C., Fink, G., Garric, J., Halling-Sørensen, B., Knacker, T., Krogh, K. A., Küster, A., Löffler, D., Cots, M. Á. P., Pope, L., Prasse, C., Römbke, J. & 8 others, Rönnefahrt, I., Schneider, M. K., Schweitzer, N., Tarazone, J. V., Ternes, T. A., Traunspurger, W., Wehrhan, A. & Duis, K., 2010, In: Integrated Environmental Assessment and Management. 6, Suppl. 1, p. 567-587

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Preliminary environmental risk assessment of the parasiticide ivermectin

    Liebig, M., Boxall, A., Duis, K., Egeler, P., Garric, J., Halling-Sørensen, B., Knacker, T., Krogh, K. A. & Küster, A., 2007.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  29. Published

    New human milk fat substitutes from butterfat to improve fat absorption

    Li, Y., Mu, Huiling, Andersen, J. E. T., Xu, X., Meyer, O. & Ørngreen, A., 2010, In: Food Research International. 43, p. 739-744

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Characterization of barley leaf tissue using direct and indirect desorption electrospray ionization imaging mass spectrometry

    Li, B., Bjarnholt, Nanna, Hansen, S. H. & Janfelt, Christian, 2011, In: Journal of Mass Spectrometry. 46, 12, p. 1241-1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Neurochemical Research. 33, 12, p. 2629-2635

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

    Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In: Journal of Neurochemistry. 117, 5, p. 824-32 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Solvent-mediated solid phase transformations of carbamazepine: effects of simulated intestinal fluid and fasted state simulated intestinal fluid

    Lehto, P., Aaltonen, J., Tenho, M., Rantanen, Jukka, Hirvonen, J., Tanninen, V. P. & Peltonen, L., 2009, In: Journal of Pharmaceutical Sciences. 98, 3, p. 985-996

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Simultaneous measurement of liquid-phase and solid-phase transformation kinetics in rotating disc and channel flow cell dissolution devices

    Lehto, P., Aaltonen, J., Niemelä, P., Rantanen, Jukka, Hirvonen, J., Tanninen, V. P. & Peltonen, L., 2008, In: Internation Journal of Pharmaceutics. 363, 1-2, p. 66-72

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

    Lehre, A. C., Rowley, N. M., Zhou, Y., Holmseth, S., Guo, C., Holen, T., Hua, R., Laake, P., Olofsson, A. M., Poblete-Naredo, I., Rusakov, D. A., Madsen, K. K., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Danbolt, N. C., 1 Jun 2011, In: Epilepsy Research. 95, 1-2, p. 70-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    (R)-(3-amino-2-fluoropropyl) phosphinic acid (AZD3355), a novel GABAB receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action

    Lehmann, A., Antonsson, M., Holmberg, A. A., Blackshaw, L. A., Brändén, L., Bräuner, Hans, Christiansen, B., Dent, J., Elebring, T., Jacobson, B., Jensen, J., Mattsson, J. P., Nilsson, K., Oja, S. S., Page, A. J., Saransaari, P. & von Unge, S., 2009, In: Journal of Pharmacology and Experimental Therapeutics. 331, 2, p. 504-512

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Particle size dependence of polymorphism in spray-dried mannitol

    Lee, Y., Wu, J., Yang, Mingshi, Young, P. M., van der Berg, Franciscus Winfried J & Rantanen, Jukka, 2011, In: European Journal of Pharmaceutical Sciences. 44, 1-2, p. 41-48

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Praktiske erfaringer med maskinel dosisdispensering af medicin (MD)

    Lee, A., Nørgaard, Lotte Stig & Herborg, H., 2007, In: Sygeplejersken. 21, p. 52-6

    Research output: Contribution to journalJournal articleResearch

  39. Published

    Design space approach in the optimization of the spray-drying process

    Lebrun, P., Krier, F., Mantanus, J., Grohganz, Holger, Yang, Mingshi, Rozet, E., Boulanger, B., Evrard, B., Rantanen, Jukka & Hubert, P., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 80, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Quantitative chemical transformations for the synthesis and modification of peptidomimetics on solid phase

    Le Quement, S. T., 2007, København: Det Farmaceutiske Fakultet. 190 p.

    Research output: Book/ReportPh.D. thesisResearch

  41. Published

    Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score

    Laustsen, A. H. & Lohse, B., 15 Sep 2015, In: Toxicon. 104, p. 43-45 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  42. Published

    Maternal intake of fish oil but not of linseed oil reduces the the antibody response in neonatal mice

    Lauritzen, Lotte, Kjær, T. M. R., Porsgaard, T., Fruekilde, M., Mu, Huiling & Frøkiær, Hanne, 2011, In: Lipids. 46, 2, p. 171-178 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Fast and direct recognition of the active ingredients in tablets using hot cell membrane inlet mass spectrometry

    Lauritsen, F. R. & Nielsen, K., 2010, In: International Journal of Mass Spectrometry. 295, p. 119-123

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Human urine as test material in 1H NMR-based metabonomics: recommendations for sample preparation and storage

    Lauridsen, M., Hansen, S. H., Jaroszewski, J. W. & Cornett, Claus, 2007, In: Analytical Chemistry. 79, 3, p. 1181-1186

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies

    Lauridsen, M., Maher, A. D., Keun, H., Lindon, J. C., Nicholson, J. K., Nyberg, N. T., Hansen, S. H., Cornett, Claus & Jaroszewski, J. W., 2008, In: Analytical Chemistry. 80, 9, p. 3365-3371

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Airway inflammation and adjuvant effect after repeated airborne exposures to di-(2-ethylhexyl)phthalate and ovalbumin in BALB/c mice.

    Larsen, S. T., Hansen, J. S., Hansen, E. W., Clausen, P. A. & Nielsen, G. D., 2007, In: Toxicology. 235, 1-2, p. 119-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Critical factors influencing the In Vivo performance of long-acting liophilic solutions - impact on In Vitro release method design

    Larsen, Susan Weng & Larsen, C. S., 2009, In: The AAPS Journal. 11, 4, p. 762-770

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Assessment of drug release from oil depot formulations using an in vitro model: Potential applicability in accelerated release testing

    Larsen, Susan Weng, Jessen, M. N. B., Østergaard, Jesper & Larsen, C. S., 2008, In: Drug Development and Industrial Pharmacy. 34, 3, p. 297-304

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds

    Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Marcher, H. & Larsen, C. S., 2008, In: European Journal of Pharmaceutical Sciences. 34, 1, p. 37-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Diflunisal salts of bupivacaine, lidocaine and morphine. Use of the common ion effect for prolonging the release of bupivacaine from mixed salt suspensions in an in vitro dialysis model

    Larsen, Susan Weng, Østergaard, Jesper, Poulsen, S., Schulz, B. & Larsen, C. S., 2007, In: European Journal of Pharmaceutical Sciences. 31, 3-4, p. 172-179

    Research output: Contribution to journalJournal articleResearchpeer-review