Research areas

  1. Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, K. A., Ringkjøbing-Elema, M., Müllertz, A., Bond, A. & Rantanen, J., 28 Oct 2010, In : Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In : Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Use of over-the-counter analgesics and perceived stress among 25-44-year olds

    Koushede, V., Holstein, B. E., Andersen, A., Ekholm, O. & Hansen, E. H., 2010, In : Pharmacoepidemiology and Drug Safety. 19, p. 351-357

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Stress and medicine use for headache: does sense of coherence modify the association?

    Koushede, V. J., Holstein, B. E., Andersen, A. & Hansen, E. H., 1 Oct 2011, In : European Journal of Public Health. 21, 5, p. 656-61 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Medicine use for headache: the effect of social class, stress and sense of coherence

    Koushede, V. J., Holstein, B., Andersen, A. & Hansen, E. H., 2010, In : International Journal of Behavioral Medicine. 17, Suppl. 1, p. s139

    Research output: Contribution to journalConference abstract in journalResearch

  6. Published

    Stress kan fordoble risikoen for at bruge smertestillende medicin

    Koushede, V. J. & Hansen, E. H., 2010, In : Lægemiddelforskning. 2010, p. 37-39

    Research output: Contribution to journalJournal articleResearch

  7. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs

    Krall, J., Jensen, C. H., Bavo, F., Falk-Petersen, Christina Birkedahl, Haugaard, A. S., Vogensen, S. B., Tian, Y., Nittegaard-Nielsen, M., Sigurdardóttir, S. B., Kehler, J., Kongstad, Kenneth Thermann, Gloriam, David E., Clausen, Rasmus Prætorius, Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 2017, In : Journal of Medicinal Chemistry. 60, 21, p. 9022-9039 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

    Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 173-178

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development

    Krishna, R., Schaefer, H. G. & Bjerrum, Ole Jannik, 2007, In : European Journal of Pharmaceutical Sciences. 31, 1, p. 62-67

    Research output: Contribution to journalLetterResearch

  10. Published

    Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating

    Kristensen, Anders Skov, Jenkins, M. A., Banke, T. G., Schousboe, Arne, Makino, Y., Johnson, R. C., Huganir, R. & Traynelis, S. F., 1 Jun 2011, In : Nature Neuroscience. 14, 6, p. 727-735

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Structural correlates of ionotropic glutamate receptor function

    Kristensen, Anders Skov, Hansen, K. B., Wollmuth, L. P., Egebjerg, J. & Traynelis, S. F., 2007, The receptors: The glutamate receptors. Gereau, R. W. & Swanson, G. T. (eds.). 1. ed. Totowa N.J., USA: Humana Press, p. 247-299 42 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  12. Published

    On-line monitoring of the dynamics of trihalomethane concentrations in a warm public swimming pool using an unsupervised membrane inlet mass spectrometry system with off-site real-time surveillance

    Kristensen, G. H., Klausen, M. M., Hansen, V. A. & Lauritsen, F. R., 2010, In : Rapid Communications in Mass Spectrometry. 24, 1, p. 30-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

    Kristensen, J. B. L., Nielsen, A. L., Jørgensen, L., Kristensen, L. H., Helgstrand, C., Juknaite, L., Kristensen, Jesper Langgaard, Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius, Olsen, L. & Gajhede, Michael, 23 Jun 2011, In : F E B S Letters. 585, 12, p. 1951-1956

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Absorption difference between diacylglycerol oil and butter blend containing deacylglycerol oil

    Kristensen, J. B., Jørgensen, H. & Mu, Huiling, 2012, In : European Journal of Lipid Science and Technology. 114, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Histonhaler: et nyt mål inden for kræftbehandling

    Kristensen, Jesper Langgaard, Lohse, Brian & Clausen, Rasmus Prætorius, Dec 2010, In : Lægemiddelforskning. 2010, p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  16. Published

    Synthesis of RHPS4 via an anionic ring closing cascade

    Kristensen, Jesper Langgaard, 2008, In : Tetrahedron Letters. 49, 15, p. 2351-2354

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity for alpha1-adrenoceptors

    Kristensen, Jesper Langgaard, Pu¨schl, A., Jensen, M., Risgaard, R., Christoffersen, C. T., Bang-Andersen, B. & Balle, T., 2010, In : Journal of Medicinal Chemistry. 53, 19, p. 7021-7034

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

    Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, Paul, Kastrup, Jette Sandholm Jensen, Helin, Kristian, Olsen, L. & Gajhede, Michael, Jun 2012, In : F E B S Journal. 279, 11, p. 1905-1914

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors

    Kristensen, L. H., 2012, København: Faculty of Health and Medical Sciences, University of Copenhagen. 168 p.

    Research output: Book/ReportPh.D. thesisResearch

  20. Published

    Stressfremkaldende hjerneaktivitet kan nu undersøges i realtid

    Kristensen, M. P., 2010, In : Lægemiddelforskning. 2010, p. 40-42

    Research output: Contribution to journalJournal articleCommunication

  21. Published

    Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp

    Kristensen, O., Ross, B. & Gajhede, Michael, 2008, In : Journal of Molecular Biology. 375, 5, p. 1469-1476

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Access to health care in relation to socioeconomic status in the Amazonian area of Peru

    Kristiansson, C., Gotuzzo, E., Rodriguez, H., Bartoloni, A., Strohmeyer, M., Tomson, G. & Hartvig, P., 2009, In : International Journal for Equity in Health. 8, p. 11-19

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Analysis of the dissipation kinetics of ivermectin at different temperatures and in four different soils

    Krogh, K. A., Jensen, G. G., Schneider, M. K., Fenner, K. & Halling-Sørensen, B., 2009, In : Chemosphere. 75, p. 1097-1104

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry

    Krogh, K. A., Björklund, B. E., Loeffler, D., Fink, G., Halling-Sørensen, B. & Ternes, T. A., 2008, In : Journal of Chromatography A. 1211, 1-2, p. 60-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Sorption and mobility of ivermectin in different soils

    Krogh, K. A., Søborg, T., Brodin, Birger & Halling-Sørensen, B., 2008, In : Journal of Environmental Quality. 37, 6, p. 2202-2211

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Veterinære lægemidler i natur og miljø: Er miljørisikovurdering god nok ?

    Krogh, K. A., Anskjær, G. G. & Halling-Sørensen, B., 2010, In : Lægemiddelforskning. 2010, p. 52-54

    Research output: Contribution to journalJournal articleResearch

  27. Published

    Tighten the concepts of oecd 106 and 307 to assess the fate of veterinary medicines

    Krogh, K. A., Jensen, G. G., Sporring, S. H. & Halling-Sørensen, B., 2007.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  28. Published

    Simultaneous determination of cytosine arabinoside, daunorubicin and etoposide in human plasma

    Krogh-Madsen, M., Hansen, S. H. & Honoré, P. H., 2010, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 878, 22, p. 1967-72 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Carbene mediated C-H insertion into phenyl piperazine and analogous structures: an approach to synthesise polycyclic, neuroactive scaffolds

    Krogsgaard-Larsen, N., 2010, København: Det Farmaceutiske Fakultet. 235 p.

    Research output: Book/ReportPh.D. thesisResearch

  30. Published

    Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion

    Krogsgaard-Larsen, N., Begtrup, M., Frydenvang, Karla Andrea & Kehler, J., 20 Nov 2010, In : Tetrahedron. 66, 47, p. 9297-9303

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands

    Krogsgaard-Larsen, N., Jensen, Anders A. & Kehler, J., 15 Sep 2010, In : Bioorganic & Medicinal Chemistry Letters. 20, 18, p. 5431-5433

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Scientific social responsibility: a call to arms

    Krogsgaard-Larsen, Povl, Thostrup, P. & Besenbacher, F., 11 Nov 2011, In : Angewandte Chemie International Edition. 50, 46, p. 10738-10740

    Research output: Contribution to journalComment/debateResearch

  33. Published

    Textbook of drug design and discovery

    Krogsgaard-Larsen, Povl, Strømgaard, Kristian & Madsen, Ulf, 2010, 4 ed. Boca Raton: CRC Press. 460 p.

    Research output: Book/ReportBookEducation

  34. Published

    Introduction to drug design and discovery

    Krogsgaard-Larsen, Povl & Bunch, Lennart, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 1-13

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  35. Published

    High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor

    Krzywkowski, K. M., Davies, P. A., Feinberg-Zadek, P. L., Bräuner-Osborne, Hans & Jensen, Anders A., 2008, In : Proceedings of the National Academy of Science of the United States of America. 105, 2, p. 722-727

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    En genetisk variation i en serotonin-receptor: et muligt link til depression?

    Krzywkowski, K. M., Davies, P. A., Feinberg-Zadek, P. L., Jensen, Anders A. & Bräuner-Osborne, Hans, 2007, In : Lægemiddelforskning. p. 30-31

    Research output: Contribution to journalJournal articleCommunication

  37. Published

    Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling

    Krzywkowski, K. M., Davies, P. A., Irving, A. J., Bräuner-Osborne, Hans & Jensen, Anders A., 2008, In : Pharmacogenetics and Genomics (Print Edition). 18, 12, p. 1027-1040

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression

    Krzywkowski, K. M., Jensen, Anders A., Connolly, C. N. & Bräuner-Osborne, Hans, 2007, In : Pharmacogenetics and Genomics (Print Edition). 17, 4, p. 255-266

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Human 5-HT3 receptors: implications of genetic variations, chaperone proteins, and subunit concatenation on function and expression

    Krzywkowski, K. M., 2008, København: Det Farmaceutiske Fakultet. 100 p.

    Research output: Book/ReportPh.D. thesisResearch

  40. Published

    Flavylium salts as in vitro precursors of potent ligands to brain GABA-A receptors

    Kueny-Stotz, M., Chassaing, S., Brouillard, R., Nielsen, M. P. C. & Goeldner, M., 2008, In : Bioorganic & Medicinal Chemistry Letters. 18, 17, p. 4864-4867

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    STELLA software as a tool for modelling phosphorus removal in a constructed wetland employing dewatered alum sludge as main substrate

    Kumar, J. L. G., Wang, Z. Y., Babatunde, A. O., Zhao, X. H. & Jørgensen, S. E., 2011, In : Journal of Environmental Science and Health. Part A: Toxic Hazardous Substances and Environmental Engineering. 46, 7, p. 751-757

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The use of Xenopus oocytes in drug screening

    Kvist, T., Hansen, K. B. & Bräuner-Osborne, Hans, 2011, In : Expert Opinion on Drug Discovery. 6, 2, p. 141-153

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    The four human ¿-aminobutyric acid (GABA) transporters: pharmacological characterization and validation of a highly efficient screening assay

    Kvist, T., Christiansen, B., Jensen, Anders A. & Bräuner-Osborne, Hans, 2009, In : Combinatorial Chemistry & High Throughput Screening. 12, 3, p. 241-249

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors

    Lager, E., Nilsson, J., Nielsen, E. Ø., Nielsen, M. P. C., Liljefors, T. & Sterner, O., 2008, In : Bioorganic & Medicinal Chemistry. 16, 14, p. 6936-6948

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Identification of natural products using HPLC-SPE combined with CapNMR

    Lambert, M., Wolfender, J., Stærk, Dan, Christensen, Søren Brøgger, Hostettmann, K. & Jaroszewski, J. W., 2007, In : Analytical Chemistry. 79, 2, p. 727-735

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Electron transfer reactivity of type zero Pseudomonas aeruginosa asurin

    Lancaster, K. M., Farver, O., Wherland, S., Crane, E. J., Richards, J. H., Pecht, I. & Gray, H. B., 2011, In : Journal of the American Chemical Society. 133, 13, p. 4865-4873

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Methods for structural characterization of prefibrillar intermediates and amyloid fibrils

    Langkilde, Annette Eva & Vestergaard, Bente, 2009, In : FEBS Letters. 583, 16, p. 2600-2609

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, Ole Jannik, Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 Apr 2011, In : European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Medicinal chemistry of competitive kainate receptor antagonists

    Larsen, A. M. & Bunch, Lennart, 16 Feb 2011, In : ACS Chemical Neuroscience. 2, 2, p. 60-74

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    The impact of an automated dose-dispensing scheme on user compliance, medication understanding, and medication stockpiles

    Larsen, A. B. & Nørgaard, Lotte Stig, 2007, In : Research in Social and Administrative Pharmacy. 3, 3, p. 265-84

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Lipid-based formulations for danazol containing a digestible surfactant, labrafil M2125CS: In vivo bioavailability and dynamic in vitro lipolysis

    Larsen, A., Holm, R., Pedersen, M. L. & Mullertz, Anette , 2008, In : Pharmaceutical Research. 25, 12, p. 2769-2777

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Selection of a lipase for development of an in vitro gastric lipid digestion model

    Larsen, A. T., Jensen, L. G., Hansen, K. K. & Mullertz, Anette , Nov 2010.

    Research output: Contribution to conferencePosterResearch

  53. Published

    In vitro lipolysis models as a tool for the characterization of oral lilpid and surfactant based drug delivery systems

    Larsen, A. T., Sassene, P. & Mullertz, Anette , 2011, In : International Journal of Pharmaceutics. 417, 1-2, p. 245-255

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Structure and function of absorption barriers

    Brodin, Birger, Steffansen, B. & Nielsen, C. U., 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage form evaluation. Steffansen, B., Brodin, B. & Nielsen, C. U. (eds.). Pharmaceutical Press, p. 115-131 (ULLA Pharmacy Series).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  55. Published

    Role of in vitro release models in formulation development and quality control of parenteral depots

    Larsen, C. S., Larsen, Susan Weng, Jensen, Henrik, Yaghmur, Anan & Østergaard, Jesper, 2009, In : Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295

    Research output: Contribution to journalReviewResearch

  56. Published

    Controlled release - macromolecular prodrugs

    Larsen, C. S., Østergaard, Jesper & Larsen, Susan Weng, 2007, Prodrugs: challenges and rewards. Stella, V. J., Borchardt, R. T., Hageman, M. J., Oliyai, R., Maag, H. & Tilley, J. W. (eds.). New York: Springer, p. 379-416

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  57. Published

    Reaction between drug substances and pharmaceutical excipients: formation of citric acid esters and amides of carvedilol in the solid state

    Larsen, J., Cornett, Claus, Jaroszewski, J. W. & Hansen, S. H., 2009, In : Journal of Pharmaceutical and Biomedical Analysis. 49, 1, p. 11-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid

    Larsen, J. T., Stærk, Dan, Cornett, Claus, Hansen, S. H. & Jaroszewski, J. W., 2009, In : Journal of Pharmaceutical and Biomedical Analysis. 49, p. 839-842

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Impurities in drugs: Analysis of drug-excipient reactions

    Larsen, J. T., 2010, Det Farmaceutiske Fakultet. 99 p.

    Research output: Book/ReportPh.D. thesisResearch

  60. Published

    Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorption in vivo following co-administration of L-tryptophan

    Larsen, M., Larsen, R., Jensen, K. G., Brodin, Birger & Nielsen, C. U., 2009, In : British Journal of Pharmacology. 157, p. 1380-1389

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: Characterization of conditions for affinity and transport experiments in Caco-2 cells.

    Larsen, M., Brodin, Birger, Frølund, Bente & Nielsen, C. U., 2008, In : European Journal of Pharmaceutical Sciences. 35, 1-2, p. 86-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Computeren er medicinalkemikerens arbejdshest

    Larsen, S. B., Olsen, L. & Jørgensen, Flemming Steen, 2009, In : Lægemiddelforskning. p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  63. Published

    Computational studies of the human peptide transporter (hPEPT1) and development of tools for virtual screening

    Larsen, S. B., 2010, København: Det Farmaceutiske Fakultet. 111 p.

    Research output: Book/ReportPh.D. thesisResearch

  64. Published

    Palladium-catalyzed monoamination of dihalogenated benzenes

    Larsen, S. B., Bang-Andersen, B., Johansen, Tommy Nørskov & Jørgensen, M., 2008, In : Tetrahedron. 64, 13, p. 2938-2950

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Discovery of ligands for the human intestinal di-/tripeptide transporter (hPEPT1) using af QSAR-assisted virtual screening strategy

    Larsen, S. B., Omkvist, Diana Højmark, Brodin, Birger, Nielsen, C. U., Steffansen, B., Olsen, L. & Jørgensen, Flemming Steen, 2009, In : ChemMedChem. 4, 9, p. 1439-1445

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Forbedret optagelse af lægemidler i organismen: computeren viser vejen

    Larsen, S. B., Jørgensen, Flemming Steen & Olsen, L., 2010, In : Dansk Kemi. 91, 6/7, p. 18-20

    Research output: Contribution to journalJournal articleResearch

  67. Published

    QSAR models for the human H+/peptide symporter, hPEPT1: Affinity prediction using alignment-independent descriptors

    Larsen, S. B., Jørgensen, Flemming Steen & Olsen, L., 2008, In : Journal of Chemical Information and Modeling. 48, 1, p. 233-241

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Critical factors influencing the In Vivo performance of long-acting liophilic solutions - impact on In Vitro release method design

    Larsen, Susan Weng & Larsen, C. S., 2009, In : The AAPS Journal. 11, 4, p. 762-770

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Assessment of drug release from oil depot formulations using an in vitro model: Potential applicability in accelerated release testing

    Larsen, Susan Weng, Jessen, M. N. B., Østergaard, Jesper & Larsen, C. S., 2008, In : Drug Development and Industrial Pharmacy. 34, 3, p. 297-304

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds

    Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Marcher, H. & Larsen, C. S., 2008, In : European Journal of Pharmaceutical Sciences. 34, 1, p. 37-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Diflunisal salts of bupivacaine, lidocaine and morphine. Use of the common ion effect for prolonging the release of bupivacaine from mixed salt suspensions in an in vitro dialysis model

    Larsen, Susan Weng, Østergaard, Jesper, Poulsen, S., Schulz, B. & Larsen, C. S., 2007, In : European Journal of Pharmaceutical Sciences. 31, 3-4, p. 172-179

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Airway inflammation and adjuvant effect after repeated airborne exposures to di-(2-ethylhexyl)phthalate and ovalbumin in BALB/c mice.

    Larsen, S. T., Hansen, J. S., Hansen, E. W., Clausen, P. A. & Nielsen, G. D., 2007, In : Toxicology. 235, 1-2, p. 119-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Human urine as test material in 1H NMR-based metabonomics: recommendations for sample preparation and storage

    Lauridsen, M., Hansen, S. H., Jaroszewski, J. W. & Cornett, Claus, 2007, In : Analytical Chemistry. 79, 3, p. 1181-1186

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies

    Lauridsen, M., Maher, A. D., Keun, H., Lindon, J. C., Nicholson, J. K., Nyberg, N. T., Hansen, S. H., Cornett, Claus & Jaroszewski, J. W., 2008, In : Analytical Chemistry. 80, 9, p. 3365-3371

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Fast and direct recognition of the active ingredients in tablets using hot cell membrane inlet mass spectrometry

    Lauritsen, F. R. & Nielsen, K., 2010, In : International Journal of Mass Spectrometry. 295, p. 119-123

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Maternal intake of fish oil but not of linseed oil reduces the the antibody response in neonatal mice

    Lauritzen, Lotte, Kjær, T. M. R., Porsgaard, T., Fruekilde, M., Mu, Huiling & Frøkiær, Hanne, 2011, In : Lipids. 46, 2, p. 171-178 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score

    Laustsen, A. H. & Lohse, Brian, 15 Sep 2015, In : Toxicon. 104, p. 43-45 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  78. Published

    Quantitative chemical transformations for the synthesis and modification of peptidomimetics on solid phase

    Le Quement, S. T., 2007, København: Det Farmaceutiske Fakultet. 190 p.

    Research output: Book/ReportPh.D. thesisResearch

  79. Published

    Design space approach in the optimization of the spray-drying process

    Lebrun, P., Krier, F., Mantanus, J., Grohganz, Holger, Yang, Mingshi, Rozet, E., Boulanger, B., Evrard, B., Rantanen, Jukka & Hubert, P., 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 80, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Praktiske erfaringer med maskinel dosisdispensering af medicin (MD)

    Lee, A., Nørgaard, Lotte Stig & Herborg, H., 2007, In : Sygeplejersken. 21, p. 52-6

    Research output: Contribution to journalJournal articleResearch

  81. Published

    Particle size dependence of polymorphism in spray-dried mannitol

    Lee, Y., Wu, J., Yang, Mingshi, Young, P. M., van der Berg, Franciscus Winfried J & Rantanen, Jukka, 2011, In : European Journal of Pharmaceutical Sciences. 44, 1-2, p. 41-48

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    (R)-(3-amino-2-fluoropropyl) phosphinic acid (AZD3355), a novel GABAB receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action

    Lehmann, A., Antonsson, M., Holmberg, A. A., Blackshaw, L. A., Brändén, L., Bräuner-Osborne, Hans, Christiansen, B., Dent, J., Elebring, T., Jacobson, B., Jensen, J., Mattsson, J. P., Nilsson, K., Oja, S. S., Page, A. J., Saransaari, P. & von Unge, S., 2009, In : Journal of Pharmacology and Experimental Therapeutics. 331, 2, p. 504-512

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

    Lehre, A. C., Rowley, N. M., Zhou, Y., Holmseth, S., Guo, C., Holen, T., Hua, R., Laake, P., Olofsson, A. M., Poblete-Naredo, I., Rusakov, D. A., Madsen, K. K., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Danbolt, N. C., 1 Jun 2011, In : Epilepsy Research. 95, 1-2, p. 70-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Solvent-mediated solid phase transformations of carbamazepine: effects of simulated intestinal fluid and fasted state simulated intestinal fluid

    Lehto, P., Aaltonen, J., Tenho, M., Rantanen, Jukka, Hirvonen, J., Tanninen, V. P. & Peltonen, L., 2009, In : Journal of Pharmaceutical Sciences. 98, 3, p. 985-996

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Simultaneous measurement of liquid-phase and solid-phase transformation kinetics in rotating disc and channel flow cell dissolution devices

    Lehto, P., Aaltonen, J., Niemelä, P., Rantanen, Jukka, Hirvonen, J., Tanninen, V. P. & Peltonen, L., 2008, In : Internation Journal of Pharmaceutics. 363, 1-2, p. 66-72

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In : Neurochemical Research. 33, 12, p. 2629-2635

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

    Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In : Journal of Neurochemistry. 117, 5, p. 824-32 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Characterization of barley leaf tissue using direct and indirect desorption electrospray ionization imaging mass spectrometry

    Li, B., Bjarnholt, Nanna, Hansen, S. H. & Janfelt, Christian, 2011, In : Journal of Mass Spectrometry. 46, 12, p. 1241-1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    New human milk fat substitutes from butterfat to improve fat absorption

    Li, Y., Mu, Huiling, Andersen, J. E. T., Xu, X., Meyer, O. & Ørngreen, A., 2010, In : Food Research International. 43, p. 739-744

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Preliminary environmental risk assessment of the parasiticide ivermectin

    Liebig, M., Boxall, A., Duis, K., Egeler, P., Garric, J., Halling-Sørensen, B., Knacker, T., Krogh, K. A. & Küster, A., 2007.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  91. Published

    Environmental risk assessment of ivermectin - A case study with a veterinary pharmaceutical

    Liebig, M., Fernandez, A. A., Blübaum-Gronau, E., Boxall, A., Duis, K., Egeler, P., Fenner, K., Fink, G., Garric, J., Halling-Sørensen, B., Jensen, J., Knacker, T., Krogh, K. A., Küster, A., Pope, L., Römbke, J., Rönnefahrt, I., Argüello, P. S., Schneider, M., Tait, A., Tarazona, J., Ternes, T. & Werhan, A., 2008, World under stress: scientific and applied issues in environmental toxicology and chemistry. Society of Environmental Toxicology and Chemistry, p. 28-28

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  92. Published

    Environmental risk assessment of ivermectin: A case study

    Liebig, M., Fernandez, Á. A., Blübaum-Gronau, E., Boxall, A., Brinke, M., Carbonell, G., Egeler, P., Fenner, K., Fernandez, C., Fink, G., Garric, J., Halling-Sørensen, B., Knacker, T., Krogh, K. A., Küster, A., Löffler, D., Cots, M. Á. P., Pope, L., Prasse, C., Römbke, J., Rönnefahrt, I., Schneider, M. K., Schweitzer, N., Tarazone, J. V., Ternes, T. A., Traunspurger, W., Wehrhan, A. & Duis, K., 2010, In : Integrated Environmental Assessment and Management. 6, Suppl. 1, p. 567-587

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Increased litter size and super-ovulation rate in congenic C57BL mice carrying a polymorphic fragment of NFR/N origin at the Fecq4 locus of chromosome 9

    Liljander, M., Andersson, Å. I. M., Holmdahl, R. & Mattsson, R., 2009, In : Genetics Research. 91, 4, p. 259-65 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Increased susceptibility to collagen-induced arthritis in female mice carrying congenic Cia40/Pregq2 fragments

    Liljander, M., Andersson, Å. I. M., Holmdahl, R. & Mattsson, R., 2008, In : Arthritis Research & Therapy. 10, 4, p. R88 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Molecular recognition in ligand-protein binding

    Liljefors, T., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 15-27

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  96. Published

    Knowledge-sharing practices in pharmaceutical research and development—a case study.

    Lilleoere, A. & Hansen, E. H., 2011, In : Knowledge and Process Management (Print Edition). 18, 3, p. 121-132 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Knowledge creation processes in researceh and development: a case study in the pharmaceutical industry

    Lilleøre, A., 2010, København: Museum Tusculanum. 67 p.

    Research output: Book/ReportPh.D. thesisResearch

  98. Published

    Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80

    Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2008, In : European Journal of Pharmaceutical Sciences. 35, 3, p. 211-218

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

    Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In : European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes

    Lindvall, T., Karlsson, J., Holmdahl, R. & Andersson, Å. I. M., 2009, In : Arthritis Research & Therapy. 11, 1, p. R10

    Research output: Contribution to journalJournal articleResearchpeer-review

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