Ling Deng

Ling Deng

Associate Professor


  1. Published

    Escherichia coli CRISPR arrays from early life fecal samples preferentially target prophages

    Dion, M. B., Shah, S. A., Deng, Ling, Thorsen, Jonathan Jan Ilve, Stokholm, Jakob, Krogfelt, K. A., Schjørring, S., Horvath, P., Allard, A., Nielsen, Dennis Sandris, Petit, M. A. & Moineau, S., 2024, In: The ISME Journal. 18, 1, 9 p., wrae005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A Protocol for Extraction of Infective Viromes Suitable for Metagenomics Sequencing from Low Volume Fecal Samples

    Deng, Ling, Silins, R., Castro-Mejia, J. L., Kot, W., Jessen, L., Thorsen, J., Shah, S., Stokholm, Jakob, Bisgaard, H., Moineau, S. & Nielsen, Dennis Sandris, 2019, In: Viruses. 11, 7, 10 p., 667.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A novel interference mechanism by a type IIIB CRISPR-Cmr module in Sulfolobus

    Deng, Ling, Garrett, Roger Antony, Shah, S. A., Peng, Xu & She, Q., 2013, In: Molecular Microbiology. 87, 5, p. 1088-1099 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A novel single-tailed fusiform Sulfolobus virus STSV2 infecting model Sulfolobus species

    Erdmann, S., Chen, B., Huang, X., Deng, Ling, Liu, C., Shah, S. A., Bauer, S. L. M., León Sobrino, C., Wang, H., Wei, Y., She, Q., Garrett, Roger Antony, Huang, L. & Lin, L., 2014, In: Extremophiles. 18, 1, p. 51-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A seed motif for target RNA capture enables efficient immune defence by a type III-B CRISPR-Cas system

    Pan, S., Li, Q., Deng, Ling, Jiang, S., Jin, X., Peng, N., Liang, Y., She, Q. & Li, Y., 2019, In: RNA Biology. 16, 9, p. 1166-1178

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A synthetic arabinose-inducible promoter confers high levels of recombinant protein expression in hyperthermophilic archaeon Sulfolobus islandicus

    Peng, N., Deng, Ling, Mei, Y., Jiang, D., Hu, Y., Awayez, M., Liang, Y. & She, Q., 2012, In: Applied and Environmental Microbiology. 78, 16, p. 5630-5637 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction

    Han, W., Li, Y., Deng, Ling, Feng, M., Peng, W., Hallstrøm, S., Zhang, J., Peng, N., Liang, Y. X., White, M. F. & She, Q., 2017, In: Nucleic Acids Research. 45, 4, p. 1983–1993 11 p., gkw1274.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Bacteriophage-mediated manipulation of the gut microbiome - promises and presents limitations

    Rasmussen, Torben Sølbeck, Koefoed, A. K., Jakobsen, Rasmus Riemer, Deng, Ling, Castro-Mejía, J. L., Brunse, Anders, Neve, H., Vogensen, Finn Kvist & Nielsen, Dennis Sandris, 2020, In: FEMS Microbiology Reviews. 44, 4, p. 507-521 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    CRISPR-Cas adaptive immune systems of the sulfolobales: unravelling their complexity and diversity

    Garrett, Roger Antony, Shah, S. A., Erdmann, S., Guannan, L., Mousaei, M., León Sobrino, C., Peng, W., Islin, S. R., Deng, Ling, Vestergaard, G., Peng, Xu & She, Q., 2015, In: Life. 5, 1, p. 783-817 35 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice

    Rasmussen, Torben Sølbeck, Koefoed, A. K., Deng, Ling, Muhammed, Musemma Kedir, Rousseau, G. M., Kot, Witold, Sprotte, S., Neve, H., Franz, C. M. A. P., Hansen, Axel Kornerup, Vogensen, Finn Kvist, Moineau, S. & Nielsen, Dennis Sandris, 2023, In: ISME Journal. 17, p. 432–442

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    CRISPR-based immune systems of the Sulfolobales: complexity and diversity

    Garrett, Roger Antony, Shah, S. A., Vestergaard, G. A., Deng, Ling, Guðbergsdóttir, S. R., Kenchappa, C. S., Erdmann, S. & She, Q., 2011, In: Biochemical Society Transactions. 39, 1, p. 51-57 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cesarean section induced dysbiosis promotes type 2 immunity but not oxazolone-induced dermatitis in mice

    Zachariassen, L. F., Ebert, M. B. B., Mentzel, Caroline M. Junker, Deng, Ling, Krych, Lukasz, Nielsen, Dennis Sandris, Stokholm, Jakob & Hansen, Camilla Hartmann Friis, 2023, In: Gut Microbes. 15, 2, 15 p., 2271151.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Characterization of the Vaginal DNA Virome in Health and Dysbiosis

    Jakobsen, Rasmus Riemer, Haahr, T., Humaidan, P., Jensen, J. S., Kot, Witold, Castro-Mejia, J. L., Deng, Ling, Leser, T. D. & Nielsen, Dennis Sandris, 2020, In: Viruses. 12, 10, 13 p., 1143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Choice of Ultrafilter Affects Recovery Rate of Bacteriophages

    Larsen, Frej Andreas Nøhr, Offersen, Simone Margaard, Li, V. R., Deng, Ling, Nielsen, Dennis Sandris & Rasmussen, Torben Sølbeck, 2023, In: Viruses. 15, 10, 12 p., 2051.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Deletion of the topoisomerase III gene in the hyperthermophilic archaeon Sulfolobus islandicus results in slow growth and defects in cell cycle control

    Li, X., Guo, L., Deng, Ling, Feng, D., Ren, Y., Chu, Y., She, Q. & Huang, L., 2011, In: Journal of Genetics and Genomics. 38, 6, p. 253-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published
  17. Published

    Donor-dependent fecal microbiota transplantation efficacy against necrotizing enterocolitis in preterm pigs

    Hui, Y., Vestergaard, G., Deng, Ling, Kot, Witold, Thymann, Thomas, Brunse, Anders & Nielsen, Dennis Sandris, 2022, In: npj Biofilms and Microbiomes. 8, 1, 12 p., 48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination

    Kihl, Pernille, Krych, Lukasz, Deng, Ling, Hansen, Lars Hestbjerg, Buschard, K., Skov, Søren, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: Plos One. 17, 4, 21 p., e0266719.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Enteral broad-spectrum antibiotics antagonize the effect of fecal microbiota transplantation in preterm pigs

    Brunse, Anders, Offersen, Simone Margaard, Mosegaard, J. J., Deng, Ling, Damborg, Peter Panduro, Nielsen, Dennis Sandris, Sangild, Per Torp, Thymann, Thomas & Nguyen, Duc Ninh, 2021, In: Gut Microbes. 13, 1, p. 1-16 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published
  21. Published

    Expanding known viral diversity in the healthy infant gut

    Shah, S. A., Deng, L., Thorsen, J., Pedersen, A. G., Dion, M. B., Castro-Mejía, J. L., Silins, R., Romme, F. O., Sausset, R., Jessen, L. E., Ndela, E. O., Hjelmsø, M., Rasmussen, M. A., Redgwell, T. A., Rodríguez, C. L., Vestergaard, G., Zhang, Y., Chawes, B., Bønnelykke, K., Sørensen, S. J. & 6 others, Bisgaard, H., Enault, F., Stokholm, Jakob, Moineau, S., Petit, M. A. & Nielsen, Dennis Sandris, 2023, In: Nature Microbiology. 8, p. 986–998

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Extraction and purification of viruses from fecal samples for metagenome and morphology analyses

    Castro-Mejía, J. L., Deng, Ling, Vogensen, Finn Kvist, Reyes, A. & Nielsen, Dennis Sandris, 2018, The Human Virome: Methods and Protocols. Moya, A. & Brocal, V. P. (eds.). Humana Press, p. 49-57 9 p. (Methods in Molecular Biology, Vol. 1838).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    Fecal filtrate transplantation protects against necrotizing enterocolitis

    Brunse, Anders, Deng, Ling, Pan, X., Hui, Y., Castro Mejia, J. L., Kot, Witold, Nguyen, Duc Ninh, Secher, Jan Bojsen-Møller, Nielsen, Dennis Sandris & Thymann, Thomas, 2022, In: The ISME Journal. 16, p. 686–694

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Formation of a viral replication focus in Sulfolobus cells infected by the rudivirus Sulfolobus islandicus rod-shaped virus 2

    Martinez Alvarez, Laura, Deng, Ling & Peng, Xu, Jul 2017, In: Journal of Virology. 91, 13, 12 p., e00486-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Genome binning of viral entities from bulk metagenomics data

    Johansen, Joachim, Plichta, D. R., Nissen, J. N., Jespersen, Marie Louise, Shah, S. A., Deng, Ling, Stokholm, Jakob, Bisgaard, H., Nielsen, Dennis Sandris, Sørensen, Søren Johannes & Rasmussen, Simon, 2022, In: Nature Communications. 13, 12 p., 965.

    Research output: Contribution to journalJournal articleResearchpeer-review

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