Dependence of lipid membrane phase transition temperature on the mismatch of protein and lipid hydrophobic thickness
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
A two-component solution theory is studied which incorporates hydrophobic matching as a major contribution to the lipid-protein interactions in biological membranes. A special geometrical constraint has been discovered which has important implications for the quantitative interpretation of physical effects to lipid-protein interactions. The theory has an advantage over conventional Landau-type phenomenological descriptions in that it accounts for phase separation. A certain class of experimental systems, photosynthetic reaction centre and antenna proteins reconstituted into synthetic lipid membranes of different hydrophobic thicknesses, are considered with a view to determining the parameters of the theory. The theoretical predictions are found to be in good agreement with experimental measurements of shifts in the phase transition temperature.
Originalsprog | Engelsk |
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Tidsskrift | European Biophysics Journal |
Vol/bind | 16 |
Udgave nummer | 1 |
Sider (fra-til) | 1-10 |
Antal sider | 10 |
ISSN | 0175-7571 |
DOI | |
Status | Udgivet - 1988 |
Eksternt udgivet | Ja |
ID: 238390765