Studies on the interaction between Salmonella enterica ser. Typhimurium and intestinal helminths in pigs

Research output: Contribution to journalJournal articlepeer-review

  • Nina Ruth Steenhard
  • Allan Knud Roepstorff
  • Dorte Lau Baggesen
  • Jaap Boes
  • Jensen, Tim Kåre
  • Bent Aasted
  • Niels Ørnbjerg
Concomitant infections with helminths and bacteria may affect the course and the resulting disease outcome of the individual infections. Salmonella, Oesophagostomum, Trichuris and Ascaris coexist naturally in pig herds in Denmark, and possible interactions were studied. Pigs in one experiment were trickle infected with low or moderate dose levels of Oesophagostomum spp. and challenge infected with S. Typhimurium. In another experiment, pigs were inoculated with S. Typhimurium followed by a challenge exposure to either Oesophagostomum, Trichuris or Ascaris. Enhancement of the Salmonella infection was not demonstrated in either experiment. The helminth effect on the pigs was modest and may explain the lack of influence on the Salmonella infection. A previous experiment with a larger Oesophagostomum infection level resulted in enhancement of the S. Typhimurium infection. A dose dependency of the interaction is therefore suggested. However, the relatively high worm burdens in the present study suggest that infection with these common pig helminths does generally not influence the course of concurrent S. Typhimurium infections under natural conditions.
Original languageEnglish
JournalVeterinary Parasitology
Volume139
Issue number1-3
Pages (from-to)158-167
Number of pages10
ISSN0304-4017
DOIs
Publication statusPublished - 2006

    Research areas

  • Former LIFE faculty - salmonella Typhimurium, Oesphagostomum, Ascaris suum, Trichuris suis, concomittant infections, pigs

ID: 8023967