Sterol evolution and the physics of membranes

Research output: Contribution to journal › Journal article › Research › peer-review

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Sterol evolution and the physics of membranes. / Nielsen, M.; Thewalt, J.; Miao, L.; Ipsen, J. H.; Bloom, M.; Zuckermann, M. J.; Mouritsen, O. G.

In: Europhysics Letters, Vol. 52, No. 3, 01.11.2000, p. 368-374.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Nielsen, M, Thewalt, J, Miao, L, Ipsen, JH, Bloom, M, Zuckermann, MJ & Mouritsen, OG 2000, 'Sterol evolution and the physics of membranes', Europhysics Letters, vol. 52, no. 3, pp. 368-374. https://doi.org/10.1209/epl/i2000-00448-8

APA

Nielsen, M., Thewalt, J., Miao, L., Ipsen, J. H., Bloom, M., Zuckermann, M. J., & Mouritsen, O. G. (2000). Sterol evolution and the physics of membranes. Europhysics Letters, 52(3), 368-374. https://doi.org/10.1209/epl/i2000-00448-8

Vancouver

Nielsen M, Thewalt J, Miao L, Ipsen JH, Bloom M, Zuckermann MJ et al. Sterol evolution and the physics of membranes. Europhysics Letters. 2000 Nov 1;52(3):368-374. https://doi.org/10.1209/epl/i2000-00448-8

Author

Nielsen, M. ; Thewalt, J. ; Miao, L. ; Ipsen, J. H. ; Bloom, M. ; Zuckermann, M. J. ; Mouritsen, O. G. / Sterol evolution and the physics of membranes. In: Europhysics Letters. 2000 ; Vol. 52, No. 3. pp. 368-374.

Bibtex

@article{4ce7effbe4274fa7a3e0a9ebe417a1ed,
title = "Sterol evolution and the physics of membranes",
abstract = "Sterols are important molecular components of the plasma membranes of eucaryotic cells. Using deuterium NMR spectroscopy in conjunction with statistical mechanical modelling, we present a unifying picture of how the evolution-engineered differences in molecular chemistry between cholesterol and its precursor lanosterol are manifested in the physical properties of model membranes in terms of molecular order and phase equilibria. Cholesterol optimizes the stability of a particular membrane phase, the liquid-ordered phase, that is a liquid and at the same time exhibits high molecular conformational order.",
author = "M. Nielsen and J. Thewalt and L. Miao and Ipsen, {J. H.} and M. Bloom and Zuckermann, {M. J.} and Mouritsen, {O. G.}",
year = "2000",
month = nov,
day = "1",
doi = "10.1209/epl/i2000-00448-8",
language = "English",
volume = "52",
pages = "368--374",
journal = "Lettere Al Nuovo Cimento",
issn = "0295-5075",
publisher = "IOP Publishing",
number = "3",

}

RIS

TY - JOUR

T1 - Sterol evolution and the physics of membranes

AU - Nielsen, M.

AU - Thewalt, J.

AU - Miao, L.

AU - Ipsen, J. H.

AU - Bloom, M.

AU - Zuckermann, M. J.

AU - Mouritsen, O. G.

PY - 2000/11/1

Y1 - 2000/11/1

N2 - Sterols are important molecular components of the plasma membranes of eucaryotic cells. Using deuterium NMR spectroscopy in conjunction with statistical mechanical modelling, we present a unifying picture of how the evolution-engineered differences in molecular chemistry between cholesterol and its precursor lanosterol are manifested in the physical properties of model membranes in terms of molecular order and phase equilibria. Cholesterol optimizes the stability of a particular membrane phase, the liquid-ordered phase, that is a liquid and at the same time exhibits high molecular conformational order.

AB - Sterols are important molecular components of the plasma membranes of eucaryotic cells. Using deuterium NMR spectroscopy in conjunction with statistical mechanical modelling, we present a unifying picture of how the evolution-engineered differences in molecular chemistry between cholesterol and its precursor lanosterol are manifested in the physical properties of model membranes in terms of molecular order and phase equilibria. Cholesterol optimizes the stability of a particular membrane phase, the liquid-ordered phase, that is a liquid and at the same time exhibits high molecular conformational order.

UR - http://www.scopus.com/inward/record.url?scp=0034310972&partnerID=8YFLogxK

U2 - 10.1209/epl/i2000-00448-8

DO - 10.1209/epl/i2000-00448-8

M3 - Journal article

AN - SCOPUS:0034310972

VL - 52

SP - 368

EP - 374

JO - Lettere Al Nuovo Cimento

JF - Lettere Al Nuovo Cimento

SN - 0295-5075

IS - 3

ER -

ID: 236896247