Regulation of skeletal muscle blood flow during exercise

Research output: Contribution to journalReviewResearchpeer-review

A number of mechanisms govern the rapid and precise changes in blood flow which occur in skeletal muscle with alterations in metabolic demand. Such mechanisms include sympathetic activity, functional sympatholysis, conducted vasodilation, flow mediated dilation, and compounds which stimulate formation of endothelium derived vasodilators. Compounds identified to be of importance in vasodilation include nitric oxide, prostacyclin, potassium, and nucleotides. In this review, we briefly describe some of the basic mechanisms and present selected contemporary contributions to the field. The main focus is on basic regulation of exercise hyperemia but aspects of training, age and sex have also been included.

Original languageEnglish
JournalCurrent Opinion in Physiology
Pages (from-to)146-155
Number of pages10
Publication statusPublished - 2019

    Research areas

  • Faculty of Science - Exercise hyperemia, Oxygen demand, Vasodilator mechanisms, Vascular function, Reactive oxygen species, Exercise training

ID: 227130406