Model of a sub-main transition in phospholipid bilayers
Research output: Contribution to journal › Journal article › Research › peer-review
A recently discovered submain phase transition in multi-lamellar bilayers of long-chain saturated diacyl phosphatidylcholines (Jorgensen, K. (1995) Biochim. Biophys. Acta 1240, 111-114) is discussed in terms of a theoretical molecular interaction model using computer simulation techniques. The model interprets the transition to be due to a decoupling of the acyl-chain melting from the melting of the pseudo-two-dimensional crystalline lattice of the P(β') phase. A two-stage melting process is predicted by the calculations suggesting that the sub-main transition involves a lattice melting whereas the acyl-chain melting takes place at a higher temperature at the main transition. The calculated heat contents of the two transitions as well as the chain-length dependence compare favorably with experimental data for multi-lamellar phosphatidylcholine lipid bilayers.
Original language | English |
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Journal | Biochimica et Biophysica Acta - Biomembranes |
Volume | 1283 |
Issue number | 2 |
Pages (from-to) | 170-176 |
Number of pages | 7 |
ISSN | 0005-2736 |
DOIs | |
Publication status | Published - 4 Sep 1996 |
- Calorimetry, Chain melting, Lattice melting, Lipid bilayer, Phospholipid, Submain phase transition, Theoretical model
Research areas
ID: 236887743