Effects of the insecticides malathion and deltamethrin on the phase behaviour of dimyristoylphosphatidylcholine multilamellar lipid bilayers

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Effects of the insecticides malathion and deltamethrin on the phase behaviour of dimyristoylphosphatidylcholine multilamellar lipid bilayers. / Sabra, M. C.; Jørgensen, K.; Mouritsen, O. G.

In: Progress in Colloid and Polymer Science, Vol. 116, 01.12.2000, p. 1-8.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Sabra, MC, Jørgensen, K & Mouritsen, OG 2000, 'Effects of the insecticides malathion and deltamethrin on the phase behaviour of dimyristoylphosphatidylcholine multilamellar lipid bilayers', Progress in Colloid and Polymer Science, vol. 116, pp. 1-8.

APA

Sabra, M. C., Jørgensen, K., & Mouritsen, O. G. (2000). Effects of the insecticides malathion and deltamethrin on the phase behaviour of dimyristoylphosphatidylcholine multilamellar lipid bilayers. Progress in Colloid and Polymer Science, 116, 1-8.

Vancouver

Sabra MC, Jørgensen K, Mouritsen OG. Effects of the insecticides malathion and deltamethrin on the phase behaviour of dimyristoylphosphatidylcholine multilamellar lipid bilayers. Progress in Colloid and Polymer Science. 2000 Dec 1;116:1-8.

Author

Sabra, M. C. ; Jørgensen, K. ; Mouritsen, O. G. / Effects of the insecticides malathion and deltamethrin on the phase behaviour of dimyristoylphosphatidylcholine multilamellar lipid bilayers. In: Progress in Colloid and Polymer Science. 2000 ; Vol. 116. pp. 1-8.

Bibtex

@article{3c957d1335904ac0be9e6525699eb845,
title = "Effects of the insecticides malathion and deltamethrin on the phase behaviour of dimyristoylphosphatidylcholine multilamellar lipid bilayers",
abstract = "The effects of the insecticides malathion and deltamethrin on the phase behaviour of multilamellar dimyristoylphosphatidylcholine (DMPC) bilayers were studied by differential scanning calorimetry. The results show that both insecticides broaden the main transition and suppress the main transition temperature. High concentrations of malathion narrow the main transition compared to lower concentrations of malathion. The Cp curves for lipid bilayers with high concentrations of malathion show several peaks in the main transition region, suggesting that more than one phase is present. For malathion interacting with DMPC multilamellar vesicles a high-temperature feature developed with increasing insecticide concentration. This was not seen for the vesicles with deltamethrin. Malathion affects the pretransition by broadening it and by lowering the transition temperature and the transition enthalpy. Small concentrations of deltamethrin make the pretransition disappear, but a minor peak in the specific heat appears at the same position for higher concentrations of deltamethrin. Although both insecticides are hydrophobic molecules their effects on DMPC multilamellar bilayers are very different. This suggests that details of the molecular structure of hydrophobic molecules are important for their nonspecific interactions with lipid bilayers.",
keywords = "Calorimetry, Deltamethrin, Lipid bilayer, Malathion, Phase behaviour",
author = "Sabra, {M. C.} and K. J{\o}rgensen and Mouritsen, {O. G.}",
year = "2000",
month = dec,
day = "1",
language = "English",
volume = "116",
pages = "1--8",
journal = "Kolloid-Zeit & Zeit f{\"u}r Polymers",
issn = "0303-402X",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Effects of the insecticides malathion and deltamethrin on the phase behaviour of dimyristoylphosphatidylcholine multilamellar lipid bilayers

AU - Sabra, M. C.

AU - Jørgensen, K.

AU - Mouritsen, O. G.

PY - 2000/12/1

Y1 - 2000/12/1

N2 - The effects of the insecticides malathion and deltamethrin on the phase behaviour of multilamellar dimyristoylphosphatidylcholine (DMPC) bilayers were studied by differential scanning calorimetry. The results show that both insecticides broaden the main transition and suppress the main transition temperature. High concentrations of malathion narrow the main transition compared to lower concentrations of malathion. The Cp curves for lipid bilayers with high concentrations of malathion show several peaks in the main transition region, suggesting that more than one phase is present. For malathion interacting with DMPC multilamellar vesicles a high-temperature feature developed with increasing insecticide concentration. This was not seen for the vesicles with deltamethrin. Malathion affects the pretransition by broadening it and by lowering the transition temperature and the transition enthalpy. Small concentrations of deltamethrin make the pretransition disappear, but a minor peak in the specific heat appears at the same position for higher concentrations of deltamethrin. Although both insecticides are hydrophobic molecules their effects on DMPC multilamellar bilayers are very different. This suggests that details of the molecular structure of hydrophobic molecules are important for their nonspecific interactions with lipid bilayers.

AB - The effects of the insecticides malathion and deltamethrin on the phase behaviour of multilamellar dimyristoylphosphatidylcholine (DMPC) bilayers were studied by differential scanning calorimetry. The results show that both insecticides broaden the main transition and suppress the main transition temperature. High concentrations of malathion narrow the main transition compared to lower concentrations of malathion. The Cp curves for lipid bilayers with high concentrations of malathion show several peaks in the main transition region, suggesting that more than one phase is present. For malathion interacting with DMPC multilamellar vesicles a high-temperature feature developed with increasing insecticide concentration. This was not seen for the vesicles with deltamethrin. Malathion affects the pretransition by broadening it and by lowering the transition temperature and the transition enthalpy. Small concentrations of deltamethrin make the pretransition disappear, but a minor peak in the specific heat appears at the same position for higher concentrations of deltamethrin. Although both insecticides are hydrophobic molecules their effects on DMPC multilamellar bilayers are very different. This suggests that details of the molecular structure of hydrophobic molecules are important for their nonspecific interactions with lipid bilayers.

KW - Calorimetry

KW - Deltamethrin

KW - Lipid bilayer

KW - Malathion

KW - Phase behaviour

UR - http://www.scopus.com/inward/record.url?scp=0034591250&partnerID=8YFLogxK

M3 - Journal article

AN - SCOPUS:0034591250

VL - 116

SP - 1

EP - 8

JO - Kolloid-Zeit & Zeit für Polymers

JF - Kolloid-Zeit & Zeit für Polymers

SN - 0303-402X

ER -

ID: 236896457