The species Cypholophus anisoneurus (Guillaumin) Friis & Wilmot-Dear, for which the new combination is made in this paper, is transferred to the genus Cypholophus from the genus Boehmeria on the grounds of the morphology of the female flowers, particularly unequal apical teeth of the female perianth and the short and markedly curved stigmas, and the crowded female flower-clusters having the distinctively red-velvety appearance, as seen in Cypholophus. Cypholophus anisoneurus is a shrub or small tree found only in the Solomon Islands and Vanuatu and known from less than ten collections. A full description, drawings and a distribution map are provided.