Combination of recreational soccer and caloric restricted diet reduces markers of protein catabolism and cardiovascular risk in patients with type 2 diabetes

Research output: Contribution to journalJournal articlepeer-review

  • M Vieira de Sousa
  • R Fukui
  • Peter Krustrup
  • S Dagogo-Jack
  • M E Rossi da Silva
Background: Moderate calorie-restricted diets and exercise training prevent loss of lean mass and cardiovascular risk. Because adherence to routine exercise recommendation is generally poor, we utilized recreational soccer training as a novel therapeutic exercise intervention in type 2 diabetes (T2D) patients.
Objective: We compared the effects of acute and chronic soccer training plus calorie-restricted diet on protein catabolism and cardiovascular risk markers in T2D. Design, setting and subjects: Fifty-one T2D patients (61.1±6.4 years, 29 females: 22 males) were randomly allocated to the soccer+diet-group (SDG) or to the dietgroup (DG). The 40-min soccer sessions were held 3 times per week for 12 weeks.
Results: Nineteen participants attended 100% of scheduled soccer sessions, and none suffered any injuries. The SDG group showed higher levels of growth hormone (GH), free fatty acids and ammonia compared with DG. After 12 weeks, insulin-like growth factor binding protein (IGFPB)-3 and glucose levels were lower in SDG, whereas insulin-like growth factor (IGF)-1/ IGFBP-3 ratio increased in both groups. After the last training session, an increase in IGF-1/ IGFBP-3 and attenuation in ammonia levels were suggestive of lower muscle protein catabolism.
Conclusions: Recreational soccer training was popular and safe, and was associated with decreased plasma glucose and IGFBP-3 levels, decreased ammoniagenesis, and increased lipolytic activity and IGF-1/IGFBP-3 ratio, all
indicative of attenuated catabolism.
Original languageEnglish
JournalJournal of Nutrition, Health and Aging
Volume21
Issue number2
Pages (from-to)180-186
Number of pages7
ISSN1279-7707
DOIs
Publication statusPublished - 2017

    Research areas

  • Faculty of Science - Soccer training, Insulin sensitivity, IGFBP-3, GH, IGF-1, Ammonia

ID: 157724226