Cell fusions in mammals

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Cell fusions in mammals. / Larsson, Lars-Inge; Bjerregaard, Bolette; Talts, Jan Fredrik.

In: Histochemistry and Cell Biology, Vol. 129, No. 5, 2008, p. 551-561.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Larsson, L-I, Bjerregaard, B & Talts, JF 2008, 'Cell fusions in mammals', Histochemistry and Cell Biology, vol. 129, no. 5, pp. 551-561. https://doi.org/10.1007/s00418-008-0411-1

APA

Larsson, L-I., Bjerregaard, B., & Talts, J. F. (2008). Cell fusions in mammals. Histochemistry and Cell Biology, 129(5), 551-561. https://doi.org/10.1007/s00418-008-0411-1

Vancouver

Larsson L-I, Bjerregaard B, Talts JF. Cell fusions in mammals. Histochemistry and Cell Biology. 2008;129(5):551-561. https://doi.org/10.1007/s00418-008-0411-1

Author

Larsson, Lars-Inge ; Bjerregaard, Bolette ; Talts, Jan Fredrik. / Cell fusions in mammals. In: Histochemistry and Cell Biology. 2008 ; Vol. 129, No. 5. pp. 551-561.

Bibtex

@article{4bb49250a1c411ddb6ae000ea68e967b,
title = "Cell fusions in mammals",
abstract = "Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defense system. Additionally, cell fusions participate in tissue repair and may be important to cancer development and progression. A large number of factors appear to regulate cell fusions, including receptors and ligands, membrane domain organizing proteins, proteases, signaling molecules and fusogenic proteins forming alpha-helical bundles that bring membranes close together. The syncytin family of proteins represent true fusogens and the founding member, syncytin-1, has been documented to be involved in fusions between placental trophoblasts, between cancer cells and between cancer cells and host ells. We review the literature with emphasis on the syncytin family and propose that syncytins may represent universal fusogens in primates and rodents, which work together with a number of other proteins to regulate cell fusion machinery.",
keywords = "Former LIFE faculty, Cell fusion, Syncytin, Cancer, Placenta, Env-W",
author = "Lars-Inge Larsson and Bolette Bjerregaard and Talts, {Jan Fredrik}",
year = "2008",
doi = "10.1007/s00418-008-0411-1",
language = "English",
volume = "129",
pages = "551--561",
journal = "Histochemistry and Cell Biology",
issn = "0948-6143",
publisher = "Springer",
number = "5",

}

RIS

TY - JOUR

T1 - Cell fusions in mammals

AU - Larsson, Lars-Inge

AU - Bjerregaard, Bolette

AU - Talts, Jan Fredrik

PY - 2008

Y1 - 2008

N2 - Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defense system. Additionally, cell fusions participate in tissue repair and may be important to cancer development and progression. A large number of factors appear to regulate cell fusions, including receptors and ligands, membrane domain organizing proteins, proteases, signaling molecules and fusogenic proteins forming alpha-helical bundles that bring membranes close together. The syncytin family of proteins represent true fusogens and the founding member, syncytin-1, has been documented to be involved in fusions between placental trophoblasts, between cancer cells and between cancer cells and host ells. We review the literature with emphasis on the syncytin family and propose that syncytins may represent universal fusogens in primates and rodents, which work together with a number of other proteins to regulate cell fusion machinery.

AB - Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defense system. Additionally, cell fusions participate in tissue repair and may be important to cancer development and progression. A large number of factors appear to regulate cell fusions, including receptors and ligands, membrane domain organizing proteins, proteases, signaling molecules and fusogenic proteins forming alpha-helical bundles that bring membranes close together. The syncytin family of proteins represent true fusogens and the founding member, syncytin-1, has been documented to be involved in fusions between placental trophoblasts, between cancer cells and between cancer cells and host ells. We review the literature with emphasis on the syncytin family and propose that syncytins may represent universal fusogens in primates and rodents, which work together with a number of other proteins to regulate cell fusion machinery.

KW - Former LIFE faculty

KW - Cell fusion

KW - Syncytin

KW - Cancer

KW - Placenta

KW - Env-W

U2 - 10.1007/s00418-008-0411-1

DO - 10.1007/s00418-008-0411-1

M3 - Journal article

C2 - 18351375

VL - 129

SP - 551

EP - 561

JO - Histochemistry and Cell Biology

JF - Histochemistry and Cell Biology

SN - 0948-6143

IS - 5

ER -

ID: 8113821