The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum

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The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum. / Huang, C.; Qian, Y.; Viana, T.; Siegumfeldt, H.; Arneborg, N.; Larsen, N.; Jespersen, L.

In: Journal of Applied Microbiology, Vol. 129, No. 2, 2020, p. 278-286.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Huang, C, Qian, Y, Viana, T, Siegumfeldt, H, Arneborg, N, Larsen, N & Jespersen, L 2020, 'The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum', Journal of Applied Microbiology, vol. 129, no. 2, pp. 278-286. https://doi.org/10.1111/jam.14621

APA

Huang, C., Qian, Y., Viana, T., Siegumfeldt, H., Arneborg, N., Larsen, N., & Jespersen, L. (2020). The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum. Journal of Applied Microbiology, 129(2), 278-286. https://doi.org/10.1111/jam.14621

Vancouver

Huang C, Qian Y, Viana T, Siegumfeldt H, Arneborg N, Larsen N et al. The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum. Journal of Applied Microbiology. 2020;129(2):278-286. https://doi.org/10.1111/jam.14621

Author

Huang, C. ; Qian, Y. ; Viana, T. ; Siegumfeldt, H. ; Arneborg, N. ; Larsen, N. ; Jespersen, L. / The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum. In: Journal of Applied Microbiology. 2020 ; Vol. 129, No. 2. pp. 278-286.

Bibtex

@article{179090296384402780fe25cb9585e366,
title = "The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum",
abstract = "Aims: The aim of the study was to investigate the antifungal effects of a quorum sensing-molecule, 2-phenylethanol, against the food spoilage moulds Penicillium expansum and Penicillium nordicum. Methods and Results: Conidial germination of the tested Penicillium spp. (three strains in total) were inhibited by treatments with 2-phenylethanol in a concentration-dependent manner. Germinated conidia was significantly reduced from 4·4–16·7{\%} at 7·5 mmol l−1 and completely inhibited at 15 mmol l−1 2-phenylethanol. Integrity of conidial cell membranes was unaffected by 2-phenylethanol resulting in reversible inhibition pattern of germination. In contrast, membrane permeability of actively growing hyphae was severely compromised, showing 63·5 – 75·7{\%} membrane damage upon treatment with 15 mmol l−1 2-phenylethanol. The overall inhibitory effect of 2-phenylethanol on colony development and growth of P. expansum and P. nordicum was additionally confirmed. Conclusions: 2-phenylethanol inhibits conidial germination and growth of P. expansum and P. nordicum in a nonlethal, reversible and concentration-dependent manner. Significance and Impact of the Study: The study indicates that 2-phenylethanol can find potential application as an antifungal agent for biological control of moulds in the food industry.",
keywords = "2-Phenylethanol, cell membrane integrity, conidial germination, mould inhibition, Penicillium spp.",
author = "C. Huang and Y. Qian and T. Viana and H. Siegumfeldt and N. Arneborg and N. Larsen and L. Jespersen",
year = "2020",
doi = "10.1111/jam.14621",
language = "English",
volume = "129",
pages = "278--286",
journal = "Letters in Applied Microbiology",
issn = "0266-8254",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - The quorum-sensing molecule 2-phenylethanol impaired conidial germination, hyphal membrane integrity and growth of Penicillium expansum and Penicillium nordicum

AU - Huang, C.

AU - Qian, Y.

AU - Viana, T.

AU - Siegumfeldt, H.

AU - Arneborg, N.

AU - Larsen, N.

AU - Jespersen, L.

PY - 2020

Y1 - 2020

N2 - Aims: The aim of the study was to investigate the antifungal effects of a quorum sensing-molecule, 2-phenylethanol, against the food spoilage moulds Penicillium expansum and Penicillium nordicum. Methods and Results: Conidial germination of the tested Penicillium spp. (three strains in total) were inhibited by treatments with 2-phenylethanol in a concentration-dependent manner. Germinated conidia was significantly reduced from 4·4–16·7% at 7·5 mmol l−1 and completely inhibited at 15 mmol l−1 2-phenylethanol. Integrity of conidial cell membranes was unaffected by 2-phenylethanol resulting in reversible inhibition pattern of germination. In contrast, membrane permeability of actively growing hyphae was severely compromised, showing 63·5 – 75·7% membrane damage upon treatment with 15 mmol l−1 2-phenylethanol. The overall inhibitory effect of 2-phenylethanol on colony development and growth of P. expansum and P. nordicum was additionally confirmed. Conclusions: 2-phenylethanol inhibits conidial germination and growth of P. expansum and P. nordicum in a nonlethal, reversible and concentration-dependent manner. Significance and Impact of the Study: The study indicates that 2-phenylethanol can find potential application as an antifungal agent for biological control of moulds in the food industry.

AB - Aims: The aim of the study was to investigate the antifungal effects of a quorum sensing-molecule, 2-phenylethanol, against the food spoilage moulds Penicillium expansum and Penicillium nordicum. Methods and Results: Conidial germination of the tested Penicillium spp. (three strains in total) were inhibited by treatments with 2-phenylethanol in a concentration-dependent manner. Germinated conidia was significantly reduced from 4·4–16·7% at 7·5 mmol l−1 and completely inhibited at 15 mmol l−1 2-phenylethanol. Integrity of conidial cell membranes was unaffected by 2-phenylethanol resulting in reversible inhibition pattern of germination. In contrast, membrane permeability of actively growing hyphae was severely compromised, showing 63·5 – 75·7% membrane damage upon treatment with 15 mmol l−1 2-phenylethanol. The overall inhibitory effect of 2-phenylethanol on colony development and growth of P. expansum and P. nordicum was additionally confirmed. Conclusions: 2-phenylethanol inhibits conidial germination and growth of P. expansum and P. nordicum in a nonlethal, reversible and concentration-dependent manner. Significance and Impact of the Study: The study indicates that 2-phenylethanol can find potential application as an antifungal agent for biological control of moulds in the food industry.

KW - 2-Phenylethanol

KW - cell membrane integrity

KW - conidial germination

KW - mould inhibition

KW - Penicillium spp.

U2 - 10.1111/jam.14621

DO - 10.1111/jam.14621

M3 - Journal article

C2 - 32097516

AN - SCOPUS:85081734729

VL - 129

SP - 278

EP - 286

JO - Letters in Applied Microbiology

JF - Letters in Applied Microbiology

SN - 0266-8254

IS - 2

ER -

ID: 240191600